General
Preferred name
LORNOXICAM
Synonyms
Ro 13-9297 ()
TS110 ()
Chlortenoxicam ()
Lornoxicam (Xefo) ()
CTX ()
NSC-759620 ()
RO-13-9297 ()
Xefo ()
Ro-139297 ()
Lorcam ()
Lornoxicam-d4 ()
P&D ID
PD001700
CAS
70374-39-9
1216527-48-8
Tags
natural product
drug
available
Drug Status
investigational
approved
Drug indication
Analgesic
Migraine
Anti-Inflammatory
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
18
AdooQ Bioactive Compound Library
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Enamine BioReference Compounds
MedChem Express Bioactive Compound Library
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
29
Properties
(calculated by RDKit )
Molecular Weight
370.98
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
2
Rotatable Bonds
2
Ring Count
3
Aromatic Ring Count
2
cLogP
2.3
TPSA
99.6
Fraction CSP3
0.08
Chiral centers
0.0
Largest ring
6.0
QED
0.84
QED
0.84
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Immunology/Inflammation
Neuroscience
Metabolic Enzyme/Protease
Target
COX-1
COX-2
PTGS1, PTGS2
COX
Endogenous Metabolite
Disease Area
rheumatology, neurology/psychiatry
Indication
osteoarthritis, sciata
MOA
cyclooxygenase inhibitor
Source data
