General
Preferred name
PENCICLOVIR
Synonyms
VSA 671 ()
BRL 39123 ()
PENCICLOVIR SODIUM ()
BRL-39123, VSA 671,NSC-759624 ()
Vectavir ()
Denavir ()
Fenistil ()
NSC-759624 ()
BRL-39123 ()
BRL-39123-D ()
Sodium penciclovir ()
P&D ID
PD001690
CAS
39809-25-1
Tags
prodrug
drug candidate
natural product
drug
available
Approved by
FDA
First approval
1996
Drug Status
approved
Drug indication
Coronavirus Disease 2019 (COVID-19)
Discovery agent
Human immunodeficiency virus infection
Antiviral
Max Phase
Phase 4
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Cell lines
3
Organisms
10
Compound Sets
22
Axon Medchem Screening Library
3385
Cayman Chemical Bioactives
22918
ChEMBL Approved Drugs
CHEMBL1540
ChEMBL Drugs
CHEMBL1540
CHEMBL2079793
Drug Repurposing Hub
DrugBank
DB00299
DrugBank Approved Drugs
DB00299
DrugCentral
2079
DrugCentral Approved Drugs
2079
DrugMAP
DMOUMDV
DMZ3WPN
DrugMAP Approved Drugs
DMOUMDV
DrugMatrix
Enamine BioReference Compounds
MedChem Express Bioactive Compound Library
HY-17424
NCATS Inxight Approved Drugs
359HUE8FJC
NIH Clinical Collections (NCC)
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
penciclovir
TargetMol Bioactive Compound Library
T1643
The Spectrum Collection
External IDs
48
Properties
(calculated by RDKit )
Molecular Weight
253.12
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
4
Rotatable Bonds
5
Ring Count
2
Aromatic Ring Count
2
cLogP
-1.31
TPSA
130.05
Fraction CSP3
0.5
Chiral centers
0.0
Largest ring
6.0
QED
0.52
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Microbiology&virology
Proteases/Proteasome
Anti-infection
Target
EBV
HCMV
HSV-1
HSV-2
VZV
Polymerase inhibitor
HSV
Antiviral
Indication
cold sore
MOA
DNA directed DNA polymerase inhibitor
Therapeutic Class
Antiviral Agents
Source data