General
Preferred name
DIMINAZENE ACETURATE
Synonyms
DIZE ()
Diminazene (aceturate) ()
Diminazene (diaceturate) ()
DIMINAZENE DIACETURATE ()
P&D ID
PD001666
CAS
536-71-0
908-54-3
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Diminazene aceturate (Diminazene diaceturate) is an anti-trypanosome agent for livestock. The main biochemical mechanism of the trypanocidal actions of Diminazene aceturate is by binding to trypanosomal kinetoplast DNA (kDNA) in a non-intercalative manner through specific interaction with sites rich in adenine-thymine base pairs. Diminazene aceturate is also an angiotensin-converting enzyme 2 (ACE2) activator and has strong and potent anti-inflammatory properties[1][2][3].
PRICE 29
DESCRIPTION Diminazene is a trypanocidal agent. (TargetMol Bioactive Compound Library)
DESCRIPTION Selective TRPM4 blocker (Tocris Bioactive Compound Library)
Cell lines
0
Organisms
2
Compound Sets
6
Cayman Chemical Bioactives
18678
MedChem Express Bioactive Compound Library
HY-12404
Selleckchem Bioactive Compound Library
diminazene-aceturate
TargetMol Bioactive Compound Library
T1145
The Spectrum Collection
Tocris Bioactive Compound Library
6705
External IDs
17
Properties
(calculated by RDKit )
Molecular Weight
515.22
Hydrogen Bond Acceptors
8
Hydrogen Bond Donors
9
Rotatable Bonds
9
Ring Count
2
Aromatic Ring Count
2
cLogP
0.78
TPSA
269.29
Fraction CSP3
0.18
Chiral centers
0.0
Largest ring
6.0
QED
0.1
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Angiotensin-converting Enzyme (ACE)
Parasite
Peroxiredoxin-5
QacR
Trypsin-1
ACE,Parasite
Primary Target
Acid-Sensing Ion Channels
MOA
Serine Protease
Blocker
Pathway
Microbiology/virology
Proteases/Proteasome
Anti-infection
Metabolic Enzyme/Protease
Source data