General
Preferred name
BETAHISTINE HYDROCHLORIDE
Synonyms
Betahistine 2HCl ()
PT-9 ()
Betahistine dihydrochloride ()
Betahistine (dihydrochloride) ()
Betahistine hcl ()
Serc-8 ()
Serc-16 ()
NSC-757397 ()
Betahistine (hydrochloride) ()
P&D ID
PD001645
CAS
5579-84-0
5638-76-6
Tags
available
drug
Drug Status
approved
Max Phase
4.0
Drug indication
Vasodilator
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Betahistine is a histamine H3 receptors inhibitor with IC50 of 1.9 μM.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
9
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
Enamine BioReference Compounds
MedChem Express Bioactive Compound Library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
18
Molecular Weight
208.05
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
3
Ring Count
1
Aromatic Ring Count
1
cLogP
1.69
TPSA
24.92
Fraction CSP3
0.38
Chiral centers
0.0
Largest ring
6.0
QED
0.82
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Immunology/Inflammation
Neuroscience
Neuronal Signaling
Target
H3 receptor
Histamine Receptor
Source data
