General
Preferred name
NARINGENIN
Synonyms
Naringetol ()
S-Dihydrogenistein ()
Pelargidanon ()
Salipurol ()
NSC 11855 ()
NSC 34875 ()
NSC 34875, S-Dihydrogenistein, NSC 11855, Salipurol ()
P&D ID
PD001602
CAS
480-41-1
13308-00-4
Tags
available
drug candidate
Drug Status
experimental
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Naringenin is the predominant flavanone in Citrus reticulata Blanco; displays strong anti-inflammatory and antioxidant activities. Naringenin has anti-dengue virus (DENV) activity.
PRICE
29
DESCRIPTION
Naringenin (NSC-11855) is a flavanone that is considered to have a bioactive effect on human health as antioxidant, free radical scavenger, antiinflammatory, carbohydrate metabolism promoter, immunity system modulater. This substance has also been shown to repair DNA.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
3
Organisms
6
Compound Sets
10
AdooQ Bioactive Compound Library
Drug Repurposing Hub
DrugBank
IPPI - DB
MedChem Express Bioactive Compound Library
Novartis Chemogenetic Library (NIBR MoA Box)
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
45
Molecular Weight
272.07
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
3
Rotatable Bonds
1
Ring Count
3
Aromatic Ring Count
2
cLogP
2.51
TPSA
86.99
Fraction CSP3
0.13
Chiral centers
1.0
Largest ring
6.0
QED
0.74
Structural alerts
1
Nonspecific/NOS
Flavonoid
Nuisance compounds
Related compounds
Custom attributes
(extracted from source data)
Pathway
NF-¦ÊB
DNA Damage/DNA Repair
Immunology/Inflammation
Metabolism
Microbiology/virology
NF-κB
Anti-infection
Cell Cycle/DNA Damage
Metabolic Enzyme/Protease
Vitamin D Related/Nuclear Receptor
Target
CYP1A2
Endogenous Metabolite
Influenza Virus
PPAR
Reactive Oxygen Species
CYP19A1, CYP1B1, ESR2, GLO1, HSD17B1
Dengue virus
Reactive Oxygen Species (ROS)
P450 (e.g. CYP17)
Member status
member
MOA
Apoptosis Inducers
Cytochrome P450 CYP3A4 Inhibitors
Antioxidants
Cell Adhesion Inhibitors
aromatase inhibitor, TRPV antagonist
Source data
