General
Preferred name
NARINGENIN
Synonyms
NSC 34875 ()
S-Dihydrogenistein ()
NSC 11855 ()
Salipurol ()
Naringetol ()
Pelargidanon ()
NSC 34875, S-Dihydrogenistein, NSC 11855, Salipurol ()
NSC-11855 ()
P&D ID
PD001602
CAS
480-41-1
13308-00-4
Tags
drug candidate
natural product
available
Drug Status
experimental
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
1
Organisms
5
Compound Sets
10
AdooQ Bioactive Compound Library
Drug Repurposing Hub
DrugBank
IPPI - DB
MedChem Express Bioactive Compound Library
Novartis Chemogenetic Library (NIBR MoA Box)
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
42
Properties
(calculated by RDKit )
Molecular Weight
272.07
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
3
Rotatable Bonds
1
Ring Count
3
Aromatic Ring Count
2
cLogP
2.51
TPSA
86.99
Fraction CSP3
0.13
Chiral centers
1.0
Largest ring
6.0
QED
0.74
Structural alerts
1
Nonspecific/NOS
Flavonoid
Nuisance compounds in cellular assays
Related compounds
Custom attributes
(extracted from source data)
Pathway
NF-¦ÊB
Metabolism
Anti-infection
Cell Cycle/DNA Damage
Immunology/Inflammation
Metabolic Enzyme/Protease
NF-κB
Vitamin D Related/Nuclear Receptor
Target
CYP1A2
CYP19A1, CYP1B1, ESR2, GLO1, HSD17B1
Dengue virus
Endogenous Metabolite
Influenza Virus
PPAR
Reactive Oxygen Species
P450 (e.g. CYP17)
Member status
member
MOA
Apoptosis Inducers
Cytochrome P450 CYP3A4 Inhibitors
Antioxidants
Cell Adhesion Inhibitors
aromatase inhibitor, TRPV antagonist
Source data
