General
Preferred name
XANTHURENIC ACID
Synonyms
8-Hydroxykynurenic acid ()
4,8-Dihydroxyquinaldic acid ()
XANTHURENATE ()
xanthurenate, 8-Hydroxykynurenic acid, 4,8-Dihydroxyquinaldic acid ()
P&D ID
PD001598
CAS
59-00-7
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Xanthurenic acid is a putative endogenous Group II metabotropic glutamate receptor agonist, on sensory transmission in the thalamus.
PRICE 29
DESCRIPTION Xanthurenic acid acts as an endogenous Group II metabotropic glutamate receptor (mGluR2 and mGluR3) agonist in transfected HEK293 cells at nanomolar concentrations. It suppresses cAMP formation in mouse cortical slices expressing mGlu2 and mGlu3 receptors. (BOC Sciences Bioactive Compounds)
DESCRIPTION Xanthurenic Acid (8-Hydroxykynurenic acid), a molecule arising from tryptophan metabolism by transamination of 3-hydroxykynurenine, activates mGlu2/3 Metabotropic glutamate receptors (mGlu2 and mGlu3). (TargetMol Bioactive Compound Library)
Compound Sets
6
BOC Sciences Bioactive Compounds
xanthurenic-acid-cas-59-00-7-375732
Cayman Chemical Bioactives
19191
MedChem Express Bioactive Compound Library
HY-W014666
Selleckchem Bioactive Compound Library
xanthurenic-acid
TargetMol Bioactive Compound Library
T3010
The Spectrum Collection
External IDs
32
Properties
(calculated by RDKit )
Molecular Weight
205.04
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
3
Rotatable Bonds
1
Ring Count
2
Aromatic Ring Count
2
cLogP
1.34
TPSA
90.65
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.65
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
Apoptosis
Endogenous Metabolite
GluR
mGluR
Pathway
Metabolism
Neuroscience
GPCR/G protein
Metabolic Enzyme/Protease
Neuronal Signaling
Source data