General
Preferred name
IODIPAMIDE
Synonyms
adipiodone ()
Iodipamide Methylglucamine Injection ()
Adipiodone Meglumine Injection ()
Iodipamic acid ()
IODIPAMIDE SODIUM ()
IODIPAMIDE MEGLUMINE ()
IODIPAMIDE SODIUM I 131 ()
Adipiodona ()
Cholografin ()
NSC-757423 ()
Cholografin Sodium ()
Sodium iodipamide ()
Iodipamide disodium salt ()
Meglumine iodipamide ()
Cavumbren ()
Biligrafin ()
Cholograf-n-methylglucamine ()
Methyl glucamine biligrafin ()
Methylglucamine iodipamide ()
Transbilix ()
Intrabilix ()
Iodipamide bis(n-methylglucamine) salt ()
Endographin ()
Iodipamide meglumine component of sinografin ()
Adipiodone meglumine ()
Meglumine adipiodone ()
Endografin ()
Bilipolinum ()
Cholografin Meglumine ()
Endocistobil ()
Iodipamide sodium i-131 ()
Radio-cholografin ()
P&D ID
PD001585
CAS
606-17-7
24360-85-8
2618-26-0
3521-84-4
Tags
available
drug
drug candidate
Approved by
FDA
First approval
1954
1982
Drug indication
Gallbladder disease
Drug Status
approved
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
TOXICITY Ionic radiocontrast agents like iodipamide are cytotoxic to renal cells. The toxic effects include apoptosis, cellular energy failure, disruption of calcium homeostasis, and disturbance of tubular cell polarity, and are thought to be linked to oxidative stress. Acute IV LD50 is 5000 mg/kg in rat, 3195 mg/kg in mouse, and 1200 mg/kg in dog.; ;
METABOLISM Hepatic.;
DESCRIPTION Iodipamide is an ionic radiopaque contrast agent. (GtoPdb)
DESCRIPTION Iodipamide is a tri-iodinated benzoate derivative and ionic dimeric contrast agent used in diagnostic imaging.
DESCRIPTION Iodipamide is a water-soluble radiographic contrast agent for cholecystography and intravenous cholangiography. It is a tri-iodinated benzoate derivative and ionic dimeric contrast agent used in diagnostic imaging. It blocks x-rays and appears opaque on x-ray film, thus it enhances the visibility of the bile ducts and gallbladder during cholangiography and cholecystography procedures. (BOC Sciences Bioactive Compounds)
DESCRIPTION Iodipamide (Iodipamic acid) is a water-soluble radiographic contrast media for intravenous cholangiography and cholecystography. (TargetMol Bioactive Compound Library)
Compound Sets
18
BOC Sciences Bioactive Compounds
iodipamide-cas-606-17-7-item-72876
ChEMBL Approved Drugs
CHEMBL1165268
CHEMBL1200350
CHEMBL3989806
ChEMBL Drugs
CHEMBL1165268
CHEMBL1200350
CHEMBL3989806
CHEMBL2104843
Drug Repurposing Hub
DrugBank
DB04711
DrugBank Approved Drugs
DB04711
DrugCentral
1455
DrugCentral Approved Drugs
1455
DrugMAP
DMXIQYS
DrugMAP Approved Drugs
DMXIQYS
Guide to Pharmacology
7400
MedChem Express Bioactive Compound Library
HY-B1292
NPC Screening Collection
Other bioactive compounds
Prestwick Chemical Library
ReFrame library
TargetMol Bioactive Compound Library
T0271
The Spectrum Collection
External IDs
63
Properties
(calculated by RDKit )
Molecular Weight
1139.51
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
4
Rotatable Bonds
9
Ring Count
2
Aromatic Ring Count
2
cLogP
6.85
TPSA
132.8
Fraction CSP3
0.2
Chiral centers
0.0
Largest ring
6.0
QED
0.16
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Indication
contrast agent
Target
ALB
Drug Derivative
MOA
radiopaque medium
Therapeutic Class
Contrast Media
Solubility
DMSO, Ethanol, Methanol
Source data