General
Preferred name
AMINACRINE
Synonyms
aminoacridine ()
Acrisorcinum ()
9-Aminoacridine ()
AMINACRINE HYDROCHLORIDE ()
Aminoacridina ()
NSC-13000 ()
NSC-7571 ()
Aminoacridine hydrochloride ()
Aminacrine hcl ()
Monacrin ()
Aminoacridine hcl ()
P&D ID
PD001576
CAS
90-45-9
148651-03-0
134-50-9
Tags
available
drug
drug candidate
Drug Status
approved
experimental
investigational
Max Phase
2.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION 9-Aminoacridine is a highly fluorescent dye, an acridine analog. It is used clinically as a topical antiseptic and experimentally as a mutagen. It is an intracellular pH indicator and a DNA intercalating agent. (BOC Sciences Bioactive Compounds)
DESCRIPTION Aminacrine is a slow-acting germicide effective against bacteria and fungi which is included in drug formulations for its anti-septic properties. It is a highly fluorescent anti-infective dye used clinically as a topical antiseptic and experimentally as a mutagen, due to its interaction with DNA. (Enamine Bioactive Compounds)
DESCRIPTION 9-Aminoacridine is a highly fluorescent anti-infective dye used clinically as a topical antiseptic and experimentally as a mutagen, due to its interaction with DNA. It is also used as an intracellular pH indicator. (TargetMol Bioactive Compound Library)
Cell lines
7
Organisms
1
Compound Sets
15
BOC Sciences Bioactive Compounds
9-aminoacridine-cas-90-45-9-item-79349
ChEMBL Drugs
CHEMBL43184
CHEMBL1330022
Drug Repurposing Hub
DrugBank
DB11561
DrugCentral
160
DrugCentral Approved Drugs
160
DrugMatrix
Enamine Bioactive Compounds
EBC-44123
Ki Database
9-aminoacridine
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
9-aminoacridine
TargetMol Bioactive Compound Library
T0289
The Spectrum Collection
External IDs
50
Properties
(calculated by RDKit )
Molecular Weight
194.08
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
0
Ring Count
3
Aromatic Ring Count
3
cLogP
2.97
TPSA
38.91
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.56
Structural alerts
1
amino_acridine_A(46)
c:1:c:2:c(:c:c:c:1):n:c:3:c(:c:2-[#7]):c:c:c:c:3
PAINS Family B
Related compounds
Custom attributes
(extracted from source data)
Target
Bacterial
HIV
Anti-infection
Pathway
Microbiology/virology
Proteases/Proteasome
Solubility
10 mM in DMSO
Source data