General
Preferred name
BERGENIN
Synonyms
Cuscutin ()
Bengenin ()
Bergenin (Cuscutin) ()
Yanbaicaisu ()
NSC-661749 ()
Bergeninum ()
NSC-757796 ()
P&D ID
PD001569
CAS
108032-11-7
477-90-7
Tags
available
drug candidate
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Bergenin is a cytoprotective and antioxidative polyphenol found in many medicinal plants. Bergenin has a wide spectrum activities such as hepatoprotective, antiinflammatory, immunomodulatory, antitumor, antiviral, and antifungal properties[1][2].
PRICE 29
DESCRIPTION Bergenin is trihydroxybenzoic acid glycoside and the C-glycoside of 4-O-methyl gallic acid.It shows a potent immunomodulatory effect. (BOC Sciences Bioactive Compounds)
DESCRIPTION Bergenin is a glycoside and a major constituent of Peltophorum plants and has diverse biological activities. It has hepatoprotective, antiinflammatory, immunomodulatory, antitumor, antiviral, and antifungal properties. (Enamine Bioactive Compounds)
DESCRIPTION Bergenin (Bengenin) is a polyphenol, which is an effective antinarcotic agent with antioxidant action. (TargetMol Bioactive Compound Library)
Cell lines
4
Organisms
0
Compound Sets
15
AdooQ Bioactive Compound Library
A10127
BOC Sciences Bioactive Compounds
bergenin-cas-477-90-7-item-84-69400
Cayman Chemical Bioactives
26406
ChEMBL Drugs
CHEMBL273019
Drug Repurposing Hub
Enamine Bioactive Compounds
EBC-44410
EU-OPENSCREEN Bioactive Compound Library
EOS100382
Mcule NIBR MoA Box Subset
MCULE-4906787678
MedChem Express Bioactive Compound Library
HY-N0017
Novartis Chemogenetic Library (NIBR MoA Box)
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
Bergenin-(Cuscutin)
TargetMol Bioactive Compound Library
T0122
The Spectrum Collection
External IDs
28
Properties
(calculated by RDKit )
Molecular Weight
328.08
Hydrogen Bond Acceptors
9
Hydrogen Bond Donors
5
Rotatable Bonds
2
Ring Count
3
Aromatic Ring Count
1
cLogP
-1.2
TPSA
145.91
Fraction CSP3
0.5
Chiral centers
5.0
Largest ring
6.0
QED
0.42
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Metabolic Enzyme/Protease
NF-¦ÊB
Apoptosis
Autophagy
Immunology/Inflammation
Microbiology/virology
NF-κB
Anti-infection
Target
Reactive Oxygen Species
IL1B, TNF
Bacterial
Fungal
Virus Protease
IL-1β
IL-6
NOD
TNF-α
Member status
member
MOA
Protein Tyrosine Phosphatase PTP-1B Inhibitors
interleukin inhibitor
Source data