General
Preferred name
ETODOLAC
Synonyms
AY-24236 ()
Etodolic acid ()
Lodine ()
Ultradol ()
Zedolac ()
Napilac ()
Eccoxolac ()
AY-24,236 ()
NIH-9918 ()
Etolyn ()
Lodine Sr ()
(rs)-etodolic acid ()
Lodine Xl ()
NSC-282126 ()
Flancox ()
Edolan ()
Ebretin ()
Etopan XL ()
Ramodar ()
Tedolan ()
Lodin xl ()
AY-24-236 ()
P&D ID
PD001509
CAS
41340-25-4
Tags
natural product
drug
available
Approved by
FDA
First approval
1991
Drug Status
investigational
approved
vet_approved
Drug indication
Anti-Inflammatory
Pain
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Etodolac is a nonsteroidal anti-inflammatory drug (NSAID).
(GtoPdb)
DESCRIPTION
Non-steroidal anti-inflammatory drug (NSAID)
(LOPAC library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
24
Axon Medchem Screening Library
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Enamine BioReference Compounds
Guide to Pharmacology
Ki Database
LOPAC library
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
NCATS Inxight Approved Drugs
NIH Clinical Collections (NCC)
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
37
Molecular Weight
287.15
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
4
Ring Count
3
Aromatic Ring Count
2
cLogP
3.38
TPSA
62.32
Fraction CSP3
0.47
Chiral centers
1.0
Largest ring
6.0
QED
0.91
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
COX
Pathway
Immunology/Inflammation
Metabolism
Neuroscience
Target
RXR-alpha
COX-2 inhibitor
Therapeutic Class
Analgesics
Source data
