General
Preferred name
FENOPROFEN
Synonyms
Fenoprofen (Calcium hydrate) ()
Fenoprofen (Calcium) ()
Fenoprofen calcium salt dihydrate ()
Fenoprofen calcium dihydrate ()
FENOPROFEN CALCIUM ()
LILLY-53858 ()
Fenoprofen calcium hydrate ()
Fenoprofen calcium salt dihydrate,Feprona dihydrate,Progesic dihydrate ()
Progesic ()
53858 ()
Nalfon ()
NSC-757813 ()
fenoprofen ()
Fenopron ()
Nalgesic ()
69323 ()
Feprona ()
Fepron ()
Fenoprofen (calcium salt hydrate) ()
P&D ID
PD001505
CAS
31879-05-7
53746-45-5
34597-40-5
56367-29-4
95907-05-4
29679-58-1
71720-56-4
Tags
natural product
drug
available
Approved by
FDA
First approval
1976
Drug Status
approved
Drug indication
Analgesic
Rheumatoid arthritis
Anti-Inflammatory
Anti-Inflammatory,Anti-Inflammatory
Max Phase
Phase 4
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Fenoprofen isa nonsteroidal anti-inflammatory drug, which is pharmacologically similar to aspirin, with similar anti-inflammatory analgesic and antipyretic actions. (GtoPdb)
DESCRIPTION Potent and selective negative allosteric modulator of mGlu2 receptors (Tocris Bioactive Compound Library)
DESCRIPTION Fenoprofen calcium hydrate is a non-steroidal anti-inflammatory drug (NSAID). (BOC Sciences Bioactive Compounds)
Compound Sets
32
AdooQ Bioactive Compound Library
A11689
BOC Sciences Bioactive Compounds
fenoprofen-cas-29679-58-1-item-306781
fenoprofen-calcium-hydrate-cas-71720-56-4-item-84-261432
Cayman Chemical Bioactives
23835
CeMM library of unique drugs (CLOUD)
ChEMBL Approved Drugs
CHEMBL1297
CHEMBL2103736
ChEMBL Drugs
CHEMBL1297
CHEMBL2103736
Concise Guide to Pharmacology 2017/18
4820
Concise Guide to Pharmacology 2019/20
4820
Concise Guide to Pharmacology 2021/22
4820
Concise Guide to Pharmacology 2023/24
4820
DrugBank
DB00573
DrugBank Approved Drugs
DB00573
DrugCentral
1154
DrugCentral Approved Drugs
1154
DrugMAP
DML5VQ0
DrugMAP Approved Drugs
DML5VQ0
DrugMatrix
Enamine BioReference Compounds
EU-OPENSCREEN Bioactive Compound Library
EOS102277
Guide to Pharmacology
4820
Ki Database
Fenoprofen
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL1297
MedChem Express Bioactive Compound Library
HY-B1456A
HY-B0288B
NCATS Inxight Approved Drugs
RA33EAC7KY
NPC Screening Collection
Other bioactive compounds
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
fenoprofen-calcium-hydrate
fenoprofen-calcium
TargetMol Bioactive Compound Library
T0184
The Spectrum Collection
Tocris Bioactive Compound Library
6926
External IDs
81
Properties
(calculated by RDKit )
Molecular Weight
242.09
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
4
Ring Count
2
Aromatic Ring Count
2
cLogP
3.67
TPSA
46.53
Fraction CSP3
0.13
Chiral centers
1.0
Largest ring
6.0
QED
0.89
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
COX
cyclooxygenase
COX-1
COX-2
Apoptosis
Melanocortin Receptor
Immunology & Inflammation related
Pathway
Immunology/Inflammation
Neuroscience
GPCR/G protein
Neuronal Signaling
MOA
cyclooxygenase inhibitor
Modulator
Primary Target
Melanocortin (MC) Receptors
Therapeutic Class
Antiinflammatory Agents
Source data