General
Preferred name
SULFADIMETHOXINE
Synonyms
Sulfadimethoxine (sodium) ()
Sulphadimethoxine ()
Sulphadimethoxine (sodium) ()
Sulfadimethoxydiazine sodium ()
SULFADIMETHOXINE SODIUM ()
4-amino-N-(2,6-dimethoxypyrimidin-4-yl)benzene-1-sulfonamide ()
Sulfadimetoxina ()
NSC-757860 ()
Madribon ()
NSC-683544 ()
Di-methox ()
Sodium sulfadimethoxine ()
Sulfadimethoxine sodium salt ()
P&D ID
PD001499
CAS
122-11-2
1037-50-9
Tags
available
drug
Approved by
FDA
Drug Status
vet_approved
approved
withdrawn
Max Phase
4.0
Drug indication
bacterial disease
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Sulfadimethoxine is a sulfonamide antibacterial compound. This class of compounds are competitive inhibitors of bacterial dihydropteroate synthase (DHPS), an enzyme in the pathway which generates the folic acid that is essential for bacterial growth.
(GtoPdb)
DESCRIPTION
Sulfadimethoxine (Sulphadimethoxine) is a sulfonamide antibiotic used to treat many infections[1][2].
PRICE
29
DESCRIPTION
Sulfadimethoxine (Sulphadimethoxine) is a sulfanilamide that is used as an anti-infective agent.
DESCRIPTION
Sulfadimethoxine sodium (Sulphadimethoxine sodium) is a sulfonamide antibiotic. Sulfadimethoxine sodium causes a displacement of Thiopental in plasma protein binding in rats. Sulfadimethoxine sodium is used in a variety of infection studies including urinary tract infections[1][2][3][4].
PRICE
29
DESCRIPTION
Sulphadimethoxine is a non-reducing glucuronide.
(BOC Sciences Bioactive Compounds)
DESCRIPTION
Sulfadimethoxine is a sulfonamide antibiotic that is active against Gram-negative and Gram-positive bacteria and other microorganisms. Sulfadimethoxine is used to treat many infections including treatment of respiratory, urinary tract, enteric, and soft tissue infections.
(Enamine Bioactive Compounds)
DESCRIPTION
PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory)
(TargetMol Bioactive Compound Library)
DESCRIPTION
Sulfadimethoxine is a antimicrobial agent, treatment of respiratory, urinary tract, enteric, and soft tissue infections
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
22
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMatrix
Enamine Bioactive Compounds
Enamine BioReference Compounds
Guide to Pharmacology
LSP-MoA library (Laboratory of Systems Pharmacology)
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
The Spectrum Collection
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
55
Molecular Weight
310.07
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
2
Rotatable Bonds
5
Ring Count
2
Aromatic Ring Count
2
cLogP
0.88
TPSA
116.43
Fraction CSP3
0.17
Chiral centers
0.0
Largest ring
6.0
QED
0.79
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Anti-infection
antibiotic
Bacterial
MOA
Antibacterial
dihydropteroate synthetase inhibitor
Indication
gram-negative bacterial infections, gram-positive bacterial infections
ATC
J01ED01
Toxicity type
dermatological
Pathway
Microbiology/virology
Source data
