General
Preferred name
SACCHARIN
Synonyms
Sweeta ()
O-Sulfobenzimide ()
O-Benzoic sulfimide ()
Saccharimide ()
Benzoic sulfimide ()
Benzoic sulfimide, O-Sulfobenzimide, O-Benzoic sulfimide, Saccharimide ()
INS-954(I) ()
INS NO.954(I) ()
E954 ()
NSC-5349 ()
Saccharinum ()
E-954(I) ()
P&D ID
PD001485
CAS
81-07-2
126987-83-5
128-44-9
Tags
available
drug candidate
Drug indication
Discovery agent
Epilepsy
Drug Status
investigational
Max Phase
3.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Saccharin is an orally active, non-caloric artificial sweeteners (NAS). Saccharin has bacteriostatic and microbiome-modulating properties[1].
PRICE 29
DESCRIPTION Saccharin is a non-nutritive artificial sweetener for sweetening foods and drinks. Saccharin has bacteriostatic and microbiome-modulating properties. It has been investigated for the treatment of Hypertension and Hyperglycemia. (Enamine Bioactive Compounds)
DESCRIPTION Saccharin (O-Sulfobenzimide) is a flavoring agent and non-nutritive sweetener. (TargetMol Bioactive Compound Library)
Cell lines
0
Organisms
2
Compound Sets
14
ChEMBL Drugs
CHEMBL310671
Concise Guide to Pharmacology 2023/24
5432
Drug Repurposing Hub
DrugBank
DB12418
DrugMAP
DMRA736
Enamine Bioactive Compounds
EBC-03311
Enamine BioReference Compounds
EU-OPENSCREEN Bioactive Compound Library
EOS102143
Guide to Pharmacology
5432
MedChem Express Bioactive Compound Library
HY-Y0272
NPC Screening Collection
Selleckchem Bioactive Compound Library
saccharin
TargetMol Bioactive Compound Library
T0889
The Spectrum Collection
External IDs
39
Properties
(calculated by RDKit )
Molecular Weight
183.0
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
0
Ring Count
2
Aromatic Ring Count
1
cLogP
0.12
TPSA
63.24
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.62
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
Bacterial
CA1, CA12, CA2, CA9
MOA
DNA polymerase inhibitor
Pathway
Microbiology/virology
Anti-infection
Source data