General
Preferred name
CHOLINE CHLORIDE
Synonyms
Choline-1,1,2,2-D4 Chloride ()
Biocolina ()
Biocoline ()
Hepacholine ()
CHOLINE ()
Choline (chloride) ()
Choline-d4 Chloride ()
Choline C-11 ()
Choline C 11 ()
FEMA NO. 4500 ()
Cloruro de colina ()
NSC-402838 ()
Hormocline ()
Lipotril ()
Chlorure de choline ()
Paresan ()
Choline (11c) ()
Choline c-11 cation ()
Choline c-11 ion ()
Choline-d9 (chloride) ()
P&D ID
PD001477
CAS
67-48-1
62-49-7
285979-70-6
61037-86-3
Tags
available
drug
Drug Status
approved
investigational
Max Phase
4.0
First approval
2012
Drug indication
prostate adenocarcinoma
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Choline chloride is an essential nutrient that activates alpha7 nicotinic receptors and has analgesic and anti-inflammatory activity. Glycerophosphoinositol choline can affect diseases such as liver disease, atherosclerosis and neurological disorders[1][2].
PRICE 29
DESCRIPTION Choline chloride is a quaternary ammonium salt used as an additive for animal feed, especially for chickens where it accelerates growth. (BOC Sciences Bioactive Compounds)
DESCRIPTION Choline is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism. It is needed for good nerve conduction throughout the CNS. Choline is also needed for gallbladder regulation, liver function and lecithin formation. It also aids in fat and cholesterol metabolism and prevents excessive fat build up in the liver. Choline has been used to mitigate the effects of Parkinsonism and tardive dyskinesia. (Enamine Bioactive Compounds)
DESCRIPTION Choline chloride (Biocoline) is a basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism. (TargetMol Bioactive Compound Library)
DESCRIPTION Choline-d4 Chloride (Choline-1,1,2,2-D4 Chloride) is a deuterated form of Choline chloride, an essential nutrient activating α7 nicotinic receptors with anti-inflammatory and analgesic activity. It impacts atherosclerosis, neurological diseases, and liver diseases. (TargetMol Bioactive Compound Library)
Compound Sets
13
BOC Sciences Bioactive Compounds
choline-chloride-cas-67-48-1-300159
Cayman Chemical Bioactives
31178
36454
ChEMBL Approved Drugs
CHEMBL282468
CHEMBL2095207
ChEMBL Drugs
CHEMBL282468
CHEMBL2095207
DrugBank
DB09277
DrugBank Approved Drugs
DB09277
DrugMatrix
Enamine Bioactive Compounds
EBC-04258
Enamine BioReference Compounds
MedChem Express Bioactive Compound Library
HY-B1337
Selleckchem Bioactive Compound Library
choline-chloride
TargetMol Bioactive Compound Library
T1039
TMIH-0149
The Spectrum Collection
External IDs
49
Properties
(calculated by RDKit )
Molecular Weight
139.08
Hydrogen Bond Acceptors
1
Hydrogen Bond Donors
1
Rotatable Bonds
2
Ring Count
0
Aromatic Ring Count
0
cLogP
-3.31
TPSA
20.23
Fraction CSP3
1.0
Chiral centers
0.0
Largest ring
0.0
QED
0.4
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
AChE
mAChR
Endogenous Metabolite
nAChR
AChR
Pathway
Neuroscience
Membrane Transporter/Ion Channel
Metabolic Enzyme/Protease
Neuronal Signaling
Source data