General
Preferred name
CARPROFEN
Synonyms
Rimadyl ()
Imadyl ()
Ridamyl ()
RO 20-5720/000 ()
NSC-297935 ()
Ro-205720000 ()
Carprofen for veterinary use ()
P&D ID
PD001437
CAS
53716-49-7
52263-47-5
Tags
natural product
drug
available
Approved by
FDA
First approval
1987
Drug Status
withdrawn
approved
vet_approved
Drug indication
Anti-Inflammatory
Pain
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Carprofen is a non-steroidal anti-inflammatory drug (NSAID), although it is no longer marketed for human use and now seems to be used exclusively by vets.
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
26
AdooQ Bioactive Compound Library
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Enamine BioReference Compounds
Guide to Pharmacology
Ki Database
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
34
Molecular Weight
273.06
Hydrogen Bond Acceptors
1
Hydrogen Bond Donors
2
Rotatable Bonds
2
Ring Count
3
Aromatic Ring Count
3
cLogP
4.16
TPSA
53.09
Fraction CSP3
0.13
Chiral centers
1.0
Largest ring
6.0
QED
0.74
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Immunology/Inflammation
Neuroscience
Autophagy
Metabolic Enzyme/Protease
Neuronal Signaling
Target
COX-2
COX
Endogenous Metabolite
FAAH
ATC
M01AE91
Therapeutic Class
Analgesics
Source data
