General
Preferred name
TRANEXAMIC ACID
Synonyms
Tranexamic ()
Tranexamsaeure ()
Amstat ()
tranexamic acid, Xenoport ()
cyclocapron ()
Transamin ()
Trans AMCHA ()
Espercil ()
Cyclokapron ()
Cyclo-f ()
CL-65336 ()
Femstrual ()
Cyklo-f Heavy Period Relief ()
Cyklokapron ()
LB-1148 ()
LB1148 ()
Exacyl ()
Menstralite ()
Rikavarin ()
TRANS-AMCHA ()
Lysteda ()
NSC-291305 ()
Haematrix ()
CL 65336 ()
Amcha ()
RP-18429 ()
Tranexamic Acid-13C2,15N ()
P&D ID
PD001423
CAS
1197-18-8
1292837-95-6
Tags
natural product
drug
available
Approved by
FDA
First approval
1986
Drug Status
approved
Max Phase
Phase 4
Drug indication
Hemostatic
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION This ligand is represented on PubChem without specified stereochemistry by CID 5526. (GtoPdb)
Cell lines
0
Organisms
1
Compound Sets
25
Cayman Chemical Bioactives
19193
28804
CeMM library of unique drugs (CLOUD)
ChEMBL Approved Drugs
CHEMBL877
ChEMBL Drugs
CHEMBL877
Concise Guide to Pharmacology 2017/18
6573
Concise Guide to Pharmacology 2019/20
6573
Concise Guide to Pharmacology 2021/22
6573
Concise Guide to Pharmacology 2023/24
6573
Drug Repurposing Hub
DrugBank
DB00302
DrugBank Approved Drugs
DB00302
DrugCentral
2713
DrugCentral Approved Drugs
2713
Enamine BioReference Compounds
Guide to Pharmacology
6573
Mcule NIBR MoA Box Subset
MCULE-6087008336
MedChem Express Bioactive Compound Library
HY-B0149
NCATS Inxight Approved Drugs
6T84R30KC1
Novartis Chemogenetic Library (NIBR MoA Box)
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
tranexamic-acid-transamin
TargetMol Bioactive Compound Library
T0949
The Spectrum Collection
External IDs
40
Properties
(calculated by RDKit )
Molecular Weight
157.11
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
2
Ring Count
1
Aromatic Ring Count
0
cLogP
0.84
TPSA
63.32
Fraction CSP3
0.88
Chiral centers
0.0
Largest ring
6.0
QED
0.62
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
MOA
Plasminogen inhibitor
Tissue-Type Plasminogen Activator (t-PA) Inhibitors
antifibrinolytic, plasminogen activator inhibitor
Target
Plasminogen
PLG
AMPK
IGF-1R
Mitophagy
MMP
Member status
member
Indication
hemophilia
Pathway
Autophagy
Epigenetics
Metabolic Enzyme/Protease
PI3K/Akt/mTOR
Protein Tyrosine Kinase/RTK
Source data