General
Preferred name
SURAMIN HEXASODIUM
Synonyms
Suramin sodium salt ()
Suramin hexasodium salt ()
SURAMIN ()
Suramin (sodium salt) ()
Suramin (hexasodium salt) ()
Nagananinum ()
BAY-205 ()
Naphuride ()
Suramin sodium ()
FOURNEAU 309 ()
FOURNEAU-309 ()
NF-060 ()
BAYER-205 ()
CI-1003 ()
NSC-758165 ()
Suraminum natricum ()
P&D ID
PD001418
CAS
129-46-4
145-63-1
Tags
drug candidate
natural product
available
Drug Status
investigational
Max Phase
Phase 3
Drug indication
Antineoplastic
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION P2X and P2Y receptor antagonist; antiparasitic; anti-tumor agent (LOPAC library)
DESCRIPTION Non-selective P2 antagonist (Tocriscreen Total)
Cell lines
0
Organisms
4
Compound Sets
9
Cayman Chemical Bioactives
11126
ChEMBL Drugs
CHEMBL413376
Ki Database
Suramin
LOPAC library
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL413376
MedChem Express Bioactive Compound Library
HY-B0879A
Selleckchem Bioactive Compound Library
suramin-sodium-salt
The Spectrum Collection
Tocriscreen Total
External IDs
20
Properties
(calculated by RDKit )
Molecular Weight
1427.94
Hydrogen Bond Acceptors
23
Hydrogen Bond Donors
6
Rotatable Bonds
16
Ring Count
8
Aromatic Ring Count
8
cLogP
-13.29
TPSA
500.73
Fraction CSP3
0.04
Chiral centers
0.0
Largest ring
6.0
QED
0.04
Structural alerts
1
historic compounds (Chemical Probes.org)
Obsolete
Related compounds
Custom attributes
(extracted from source data)
Selectivity
P2X, P2Y
Target
Interleukin Related
Parasite
phosphatase
Reverse Transcriptase
SARS-CoV
Sirtuin
Topoisomerase
DNA/RNA Synthesis,Sirtuin,Topoisomerase
Pathway
Immunology/Inflammation
Anti-infection
Apoptosis
Cell Cycle/DNA Damage
Epigenetics
Metabolic Enzyme/Protease
Source data