General
Preferred name
PD001392
Synonyms
5-FLUOROINDOLE-2-CARBOXYLIC ACID ()
5-fluoro-1H-indole-2-carboxylic acid ()
5-Fluroindole-2-carboxylic acid ()
P&D ID
PD001392
CAS
399-76-8
42169-77-7
Tags
available
drug candidate
Drug indication
Glioma
Melanoma
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION 5-Fluroindole-2-carboxylic acid exhibits binding affinity to ionotropic glutamate NMDA receptor. (Enamine Bioactive Compounds)
DESCRIPTION Competitive inhibitor of potentiation by glycine at the NMDA glutamate receptor (LOPAC library)
Cell lines
0
Organisms
2
Compound Sets
6
DrugMAP
DM9U1HV
DrugMatrix
Enamine Bioactive Compounds
EBC-03545
EU-OPENSCREEN Bioactive Compound Library
EOS102274
LOPAC library
The Spectrum Collection
External IDs
24
Properties
(calculated by RDKit )
Molecular Weight
179.04
Hydrogen Bond Acceptors
1
Hydrogen Bond Donors
2
Rotatable Bonds
1
Ring Count
2
Aromatic Ring Count
2
cLogP
2.01
TPSA
53.09
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.7
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Selectivity
NMDA-Glycine
Source data