General
Preferred name
CISPLATIN
Synonyms
CDDP ()
cis-Diammineplatinum(II) dichloride ()
cis-Diaminodichloroplatinum ()
Cisplatinum ()
Lederplatin ()
Briplatin ()
Cismaplat ()
P&D ID
PD001382
CAS
14283-03-5
15663-27-1
Tags
available
contains metal
inorganic
drug
Drug indication
Osteosarcoma
Solid tumour/cancer
Drug Status
approved
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Antitumor antibiotic agent. Inhibits DNA topoisomerase II (Tocris Bioactive Compound Library)
Compound Sets
8
DrugMAP
DMRHGI9
DrugMAP Approved Drugs
DMRHGI9
DrugMatrix
LINCS compound set
10245-101
TargetMol Bioactive Compound Library
T1564
The Spectrum Collection
Tocris Bioactive Compound Library
2251
Welcome Trust Cancer Drugs
1005
External IDs
35
Properties
(calculated by RDKit )
Molecular Weight
298.96
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
0
Ring Count
0
Aromatic Ring Count
0
cLogP
1.7
TPSA
70.0
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
0.0
QED
0.71
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Pathway
DNA replication
DNA Damage/DNA Repair
Target
DNA crosslinker
DNA synthesis
Primary Target
Caspases
MOA
Activator
DNA/RNA Synthesis
Therapeutic Class
Anticancer Agents
Source data