General
Preferred name
VINBURNINE
Synonyms
Eburnalritardo ()
L-Eburnamonine ()
Vincamone ()
(-)-Eburnamonine ()
(-)-Vincamone ()
Eburnamonine (-) ()
(-)-Vincamone(-)-Eburnamonine ()
Vinburnina ()
Eburnamonine (-)-form ()
NSC-322920 ()
3.alpha.,16.alpha.-eburnamonine ()
P&D ID
PD001342
CAS
4880-88-0
Tags
available
drug
Drug indication
Discovery agent
Cardiovascular disease
Drug Status
approved
experimental
investigational
Max Phase
2.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Vincamone is a vinca alkaloid and a metabolite of vincamine, is a vasodilator.
PRICE 29
DESCRIPTION Vinburnine (Eburnalritardo) is a vasodilator. Vinburnine is a vinca alkaloid and a metabolite of vincamine. (TargetMol Bioactive Compound Library)
Cell lines
1
Organisms
0
Compound Sets
11
Cayman Chemical Bioactives
37569
ChEMBL Drugs
CHEMBL1892145
Drug Repurposing Hub
DrugBank
DB13793
DrugCentral
2824
DrugCentral Approved Drugs
2824
DrugMAP
DMO4GBK
Guide to Pharmacology
345
MedChem Express Bioactive Compound Library
HY-B1180
NPC Screening Collection
TargetMol Bioactive Compound Library
T2149
External IDs
34
Properties
(calculated by RDKit )
Molecular Weight
294.17
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
0
Rotatable Bonds
1
Ring Count
5
Aromatic Ring Count
2
cLogP
3.77
TPSA
25.24
Fraction CSP3
0.53
Chiral centers
2.0
Largest ring
6.0
QED
0.8
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Drug Metabolite
CHRM1, CHRM2, CHRM3, CHRM4
mAChR
Indication
stroke
MOA
Adrenergic Receptor antagonist
Pathway
Metabolism
GPCR/G protein
Metabolic Enzyme/Protease
Neuronal Signaling
Source data