General
Preferred name
FISETIN
Synonyms
Fisetin (Fustel) ()
3,7,3',4'-TETRAHYDROXYFLAVONE ()
Fisetin (Standard) ()
Fisidenolon 1521 ()
C.i. natural brown 1 ()
5-desoxyquercetin ()
NSC-656275 ()
NSC-407010 ()
C.i. 75620 ()
Fisetin-d5 ()
P&D ID
PD001338
CAS
528-48-3
2909407-29-8
Tags
available
obsolete probe
drug candidate
nuisance
natural product
Drug indication
Discovery agent
Drug Status
experimental
investigational
Max Phase
Phase 2
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Potent and selective inhibitor of L-type amino acid transporter 1 (LAT1); active in vivo (Tocris Bioactive Compound Library)
Cell lines
8
Organisms
4
Compound Sets
17
AdooQ Bioactive Compound Library
A10388
Cayman Chemical Bioactives
15246
34706
ChEMBL Drugs
CHEMBL31574
Drug Repurposing Hub
DrugBank
DB07795
DrugMAP
DMES906
Guide to Pharmacology
5182
MedChem Express Bioactive Compound Library
HY-N0182
HY-N0182R
NIH Mechanistic Set
Nuisance compounds in cellular assays
Obsolete Compounds
fisetin
ReFrame library
Selleckchem Bioactive Compound Library
Fisetin(Fustel)
TargetMol Bioactive Compound Library
T2879
The Spectrum Collection
Tocris Bioactive Compound Library
5016
ZINC Tool Compounds
ZINC000000039111
External IDs
39
Properties
(calculated by RDKit )
Molecular Weight
286.05
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
4
Rotatable Bonds
1
Ring Count
3
Aromatic Ring Count
3
cLogP
2.28
TPSA
111.13
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.51
Structural alerts
4
aggregator (Aggregator Advisor)
Aggregators
aggregator (ZINC)
Aggregators
Nonspecific/NOS
Flavonoid
Nuisance compounds in cellular assays
historic compounds (Chemical Probes.org)
Obsolete
Related compounds
Custom attributes
(extracted from source data)
Pathway
Chromatin/Epigenetic
DNA Damage/DNA Repair
Apoptosis
Cell Cycle/DNA Damage
Epigenetics
Vitamin D Related/Nuclear Receptor
Target
SIRT
CDK6, FASN
PPAR
Sirtuin
TNF Receptor
Primary Target
Antioxidants
MOA
Aurora Kinase inhibitor
Source data