General
Preferred name
BUTOCONAZOLE
Synonyms
RS 35887 ()
BUTOCONAZOLE NITRATE ()
Butoconazole (nitrate) ()
RS-35887 ()
Gynofort ()
Gynazole-1 ()
NSC-758658 ()
RS-35887-00-10-3 ()
Femstat 3 ()
Gynazole ()
Femstat ()
P&D ID
PD001266
CAS
64872-77-1
64872-76-0
67085-14-7
67085-13-6
32872-77-1
Tags
natural product
drug
available
Approved by
FDA
First approval
1995
1985
Drug Status
approved
Drug indication
Candidiasis
Antifungal
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
1
Compound Sets
18
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
NCATS Inxight Approved Drugs
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
57
Properties
(calculated by RDKit )
Molecular Weight
410.02
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
0
Rotatable Bonds
7
Ring Count
3
Aromatic Ring Count
3
cLogP
6.64
TPSA
17.82
Fraction CSP3
0.21
Chiral centers
1.0
Largest ring
6.0
QED
0.41
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Endocrinology/Hormones
Anti-infection
Target
ER
Fungal
Fungal,IFN,Interleukins,TNF-alpha
MOA
Estrogen/progestogen Receptor inhibitor
Therapeutic Class
Antifungal Agents
Source data
