General
Preferred name
DIRITHROMYCIN
Synonyms
LY237216 ()
ASE 136 ()
Dirithromycine ()
Dirithromycinum ()
Diritromicina ()
LY 237216 ()
NSC-758672 ()
Dynabac ()
LY-237216 ()
P&D ID
PD001262
CAS
62013-04-1
Tags
prodrug
natural product
drug
available
Approved by
FDA
First approval
1995
Drug indication
Bacterial infection
Drug Status
experimental
approved
withdrawn
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
1
Compound Sets
14
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Prestwick Chemical Library
ReFrame library
TargetMol Bioactive Compound Library
The Spectrum Collection
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
26
Properties
(calculated by RDKit )
Molecular Weight
834.55
Hydrogen Bond Acceptors
16
Hydrogen Bond Donors
5
Rotatable Bonds
12
Ring Count
4
Aromatic Ring Count
0
cLogP
2.2
TPSA
196.33
Fraction CSP3
0.98
Chiral centers
20.0
Largest ring
14.0
QED
0.14
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Microbiology&virology
Target
50S ribosome
70S ribosome
Indication
bronchitis
MOA
bacterial 50S ribosomal subunit inhibitor
ATC
J01FA13
Therapeutic Class
Antibiotics
Source data
