General
Preferred name
MELOXICAM
Synonyms
Movalis ()
Mobic ()
Metacam ()
Meloxicam (Mobic) ()
Meloxicam71125-38-7 ()
Melovem ()
Novaquin ()
Contacera ()
Coxicam ()
N-1539 ()
Emdocam ()
Loxitab ()
Recocam ()
UHAC-62XX ()
Acticam ()
Anjeso ()
Melfax ()
Meloxivet ()
Revitacam ()
Rheumocam ()
Meloxidolor ()
Inflacam ()
Flexicam ()
UH-AC 62XX ()
Meloxicam component of zeleris ()
Qmiiz odt ()
Meloxicam component of zynrelef ()
Vivlodex ()
Loxicom ()
Melosus ()
Meloxidyl ()
Movatec ()
Meloxoral ()
UH-AC-62 XX ()
Novem ()
N1539 ()
Meloxicam-d3 ()
P&D ID
PD001257
CAS
71125-38-7
942047-63-4
Tags
available
drug
Approved by
FDA
First approval
2000
Drug indication
Arthritis
Pain
Drug Status
vet_approved
approved
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Meloxicam is a non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic actions. (GtoPdb)
PRICE 29
DESCRIPTION Meloxicam is a non-steroidal antiinflammatory agent, inhibits COX activity, with IC50s of 0.49 ¦ÌM and 36.6 ¦ÌM for COX-2 and COX-1, respectively.
DESCRIPTION Meloxicam inhibits prostaglandin synthetase enzymes leading to a decreased synthesis of prostaglandins, which normally mediate painful inflammatory symptoms. Meloxicam is a nonsteroidal anti-inflammatory drug used to relieve various types of pain, including pain caused by musculoskeletal conditions, osteoarthritis, and rheumatoid arthritis. (Enamine Bioactive Compounds)
DESCRIPTION Meloxicam (Metacam) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of meloxicam is as a Cyclooxygenase Inhibitor. The chemical classification of meloxicam is Nonsteroidal Anti-inflammatory Compounds. (TargetMol Bioactive Compound Library)
Compound Sets
25
AdooQ Bioactive Compound Library
A10565
Cayman Chemical Bioactives
14906
40657
25508
ChEMBL Approved Drugs
CHEMBL599
ChEMBL Drugs
CHEMBL599
Concise Guide to Pharmacology 2017/18
7220
Concise Guide to Pharmacology 2019/20
7220
Drug Repurposing Hub
DrugBank
DB00814
DrugBank Approved Drugs
DB00814
DrugCentral
1676
DrugCentral Approved Drugs
1676
DrugMAP
DM2AR7L
DrugMAP Approved Drugs
DM2AR7L
DrugMatrix
Enamine Bioactive Compounds
EBC-12958
Guide to Pharmacology
7220
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL599
MedChem Express Bioactive Compound Library
HY-B0261
NCATS Inxight Approved Drugs
VG2QF83CGL
NIH Clinical Collections (NCC)
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
Meloxicam(Mobic)
TargetMol Bioactive Compound Library
T0826
The Spectrum Collection
External IDs
67
Properties
(calculated by RDKit )
Molecular Weight
351.03
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
2
Rotatable Bonds
2
Ring Count
3
Aromatic Ring Count
2
cLogP
1.95
TPSA
99.6
Fraction CSP3
0.14
Chiral centers
0.0
Largest ring
6.0
QED
0.86
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Apoptosis
Autophagy
Immunology/Inflammation
Neuroscience
Metabolic Enzyme/Protease
Indication
osteoarthritis, rheumatoid arthritis
Target
PTGS1, PTGS2
COX
MMP
MOA
cyclooxygenase inhibitor
Source data