General
Preferred name
BOVINOCIDIN
Synonyms
3-Nitropropionic Acid ()
¦Â-Nitropropionic acid ()
3-NP acid ()
3-NP ()
β-Nitropropionic acid ()
β-Nitropropionic Acid, 3-NP ()
??Nitropropionic acid ()
??Nitropropionic Acid, 3-NP ()
3-nitropropionate ()
3-Nitropropanoic acid ()
¦Â-Nitropropionic Acid, 3-NP ()
P&D ID
PD001234
CAS
504-88-1
Tags
available
drug candidate
Drug indication
Discovery agent
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION 3-Nitropropanoic acid (¦Â-Nitropropionic acid) is an irreversible and orally active inhibitor of succinate dehydrogenase. 3-Nitropropanoic acid exhibits potent antimycobacterial activity with a MIC value of 3.3 ¦ÌM. 3-Nitropropanoic acid can induce cell apoptosis[1][2].
PRICE 29
DESCRIPTION Mitochondrial inhibitor; excitotoxin shown to cause brain lesions similar to those of Huntington's disease (LOPAC library)
DESCRIPTION 3-Nitropropanoic acid (Bovinocidin) is an irreversible inhibitor of succinate dehydrogenase. (TargetMol Bioactive Compound Library)
DESCRIPTION Hedgehog acyltransferase (Hhat) inhibitor; cell permeable (Tocris Bioactive Compound Library)
Compound Sets
7
Cayman Chemical Bioactives
14684
DrugMAP
DMH798G
LOPAC library
MedChem Express Bioactive Compound Library
HY-W012875
Selleckchem Bioactive Compound Library
3-nitropropionic-acid
TargetMol Bioactive Compound Library
T3009
Tocris Bioactive Compound Library
4849
External IDs
40
Properties
(calculated by RDKit )
Molecular Weight
119.02
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
3
Ring Count
0
Aromatic Ring Count
0
cLogP
-0.26
TPSA
80.44
Fraction CSP3
0.67
Chiral centers
0.0
Largest ring
0.0
QED
0.41
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
Apoptosis
Bacterial
Dehydrogenase
Autophagy
Primary Target
Oxidative Phosphorylation
MOA
Inhibitor
Pathway
Metabolism
Microbiology/virology
Anti-infection
Source data