General
Preferred name
CLARITHROMYCIN
Synonyms
A-56268 ()
Erythromycin, 6-o-methyl- ()
Biaxin Xl ()
Klaricid Adult ()
Mycifor XL ()
Clarie XL ()
Prevpac ()
6-o-methylerythromycin ()
Biaxin Xl Pac ()
Zeclar ()
Klaricid I.V. ()
Clarithromycin identity ()
Febzin XL ()
Klaricid ()
Klaricid XL ()
Klacid ()
Clarithromycin Extended Release ()
Mavid ()
TE-031 ()
Biaxin ()
Clarosip ()
Cyllind ()
Klaricid Paed ()
ABBOTT-56268 ()
Xetinin XL ()
Macladin ()
Veclam ()
NSC-758704 ()
Klaricid 500 ()
Clarithromycin-13C-d3 ()
P&D ID
PD001219
CAS
81103-11-9
116836-41-0
2699608-30-3
Tags
natural product
drug
available
Approved by
FDA
First approval
1991
Drug Status
approved
Drug indication
Bacterial infection
Antibacterial
Max Phase
Phase 4
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Clarithromycin is a semisynthetic macrolide antibacterial. Structurally it is the 6-O-methyl ether of erythromycin A. (GtoPdb)
Cell lines
0
Organisms
3
Compound Sets
22
AdooQ Bioactive Compound Library
A10225
Axon Medchem Screening Library
3445
Cayman Chemical Bioactives
19455
26678
ChEMBL Approved Drugs
CHEMBL1741
ChEMBL Drugs
CHEMBL1741
Drug Repurposing Hub
DrugBank
DB01211
DrugBank Approved Drugs
DB01211
DrugCentral
668
DrugCentral Approved Drugs
668
DrugMAP
DM4M1SG
DrugMAP Approved Drugs
DM4M1SG
Enamine BioReference Compounds
Guide to Pharmacology
10903
MedChem Express Bioactive Compound Library
HY-17508
NCATS Inxight Approved Drugs
H1250JIK0A
NIH Clinical Collections (NCC)
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
clarithromycin
TargetMol Bioactive Compound Library
T1434
The Spectrum Collection
External IDs
50
Properties
(calculated by RDKit )
Molecular Weight
747.48
Hydrogen Bond Acceptors
14
Hydrogen Bond Donors
4
Rotatable Bonds
8
Ring Count
3
Aromatic Ring Count
0
cLogP
2.44
TPSA
182.91
Fraction CSP3
0.95
Chiral centers
18.0
Largest ring
14.0
QED
0.27
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Immunology/Inflammation
Microbiology&virology
Anti-infection
Autophagy
Metabolic Enzyme/Protease
Target
MRP1
50S ribosome
CYP3A4
antibiotic
Bacterial
Cytochrome P450
P450 (e.g. CYP17)
Indication
pharyngitis, tonsillitis, sinusitis, bronchitis, pneumonia, skin infections, otitis
Disease Area
otolaryngology, pulmonary, infectious disease
MOA
bacterial 50S ribosomal subunit inhibitor
Therapeutic Class
Antibiotics
Source data