General
Preferred name
PD001218
Synonyms
2,3-DIHYDROXY-6,7-DICHLOROQUINOXALINE ()
6,7-Dichloroquinoxaline-2,3-dione ()
6,7-Dichloro-1,4-dihydro-quinoxaline-2,3-dione ()
P&D ID
PD001218
CAS
25983-13-5
Tags
available
drug candidate
Drug indication
Discovery agent
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
High affinity antagonist specific for the strychnine-insensitive glycine binding site of the NMDA glutamate receptor
(LOPAC library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
4
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
35
Molecular Weight
229.96
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
2
Rotatable Bonds
0
Ring Count
2
Aromatic Ring Count
2
cLogP
2.35
TPSA
66.24
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.73
Structural alerts
2
aggregator (Aggregator Advisor)
Aggregators
aggregator (ZINC)
Aggregators
Related compounds
Custom attributes
(extracted from source data)
Selectivity
NMDA-Glycine
Source data
