General
Preferred name
GATIFLOXACIN
Synonyms
Gatifloxacin (mesylate) ()
AM 1155 mesylate ()
BMS 206584-01 mesylate ()
PD 135432 mesylate ()
AM 1155 hydrochloride ()
BMS 206584-01 hydrochloride ()
PD 135432 hydrochloride ()
AM-1155 (hydrochloride) ()
BMS-206584 (hydrochloride) ()
PD135432 (hydrochloride) ()
AM-1155 ()
PD 135432 ()
BMS 206584-01 ()
CG5501 ()
BMS-206584 ()
Gatifloxacin hydrochloride ()
GATIFLOXACIN ANHYDROUS ()
Gatifloxacin (hydrochloride) ()
PD135432 ()
AM-1155, CG5501, BMS-206584 ()
AM-1155 hydrochloride, CG5501 hydrochloride, BMS-206584 hydrochloride, PD135432 hydrochloride ()
Gatifloxacin mesylate ()
Gatifloxacin hydrate ()
NSC-758701 ()
Zymaxid ()
Zymar ()
BMS-206584-01 ()
Gatifloxacin sesquihydrate ()
BMS-20658401 ()
Gatifloxacin (sesquihydrate) ()
Tequin ()
PD-135432 ()
Zymer ()
Gatiflo ()
gatifloxacin ()
P&D ID
PD001202
CAS
121577-32-0
112811-59-3
160738-57-8
316819-28-0
Tags
natural product
drug
available
Approved by
FDA
First approval
1999
2003
Drug Status
investigational
approved
withdrawn
Drug indication
Antibacterial
Respiratory tract infection
Max Phase
Phase 4
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Gatifloxacin is a synthetic fourth-generation fluoroquinolone antibacterial with broad-spectrum activity against Gram-negative and Gram-positive pathogens. (GtoPdb)
DESCRIPTION Gatifloxacin (mesylate) is an antibiotic of the fourth-generation fluoroquinolone family, it inhibits the bacterial enzymes DNA gyrase and topoisomerase IV. (BOC Sciences Bioactive Compounds)
DESCRIPTION Gatifloxacin (hydrochloride) is an antibiotic of the fourth-generation fluoroquinolone family, it inhibits the bacterial enzymes DNA gyrase and topoisomerase IV. (BOC Sciences Bioactive Compounds)
Cell lines
1
Organisms
3
Compound Sets
26
AdooQ Bioactive Compound Library
A10419
Axon Medchem Screening Library
3171
BOC Sciences Bioactive Compounds
gatifloxacin-mesylate-cas-316819-28-0-item-84-107484
gatifloxacin-hydrochloride-cas-121577-32-0-item-84-55811
Cayman Chemical Bioactives
14290
ChEMBL Approved Drugs
CHEMBL31
ChEMBL Drugs
CHEMBL31
DrugBank
DB01044
DrugBank Approved Drugs
DB01044
DrugCentral
1280
DrugCentral Approved Drugs
1280
DrugMAP
DMSL679
DrugMAP Approved Drugs
DMSL679
DrugMatrix
EU-OPENSCREEN Bioactive Compound Library
EOS102146
Guide to Pharmacology
10816
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL31
MedChem Express Bioactive Compound Library
HY-10581
HY-10581A
NCATS Inxight Approved Drugs
81485Y3A9A
NIH Clinical Collections (NCC)
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
Gatifloxacin
gatifloxacin-hydrochloride
TargetMol Bioactive Compound Library
T1293
T8384
The Spectrum Collection
Withdrawn 2.0
w163
External IDs
60
Properties
(calculated by RDKit )
Molecular Weight
375.16
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
2
Rotatable Bonds
4
Ring Count
4
Aromatic Ring Count
2
cLogP
1.98
TPSA
83.8
Fraction CSP3
0.47
Chiral centers
1.0
Largest ring
6.0
QED
0.85
Structural alerts
2
aggregator (Aggregator Advisor)
Aggregators
aggregator (ZINC)
Aggregators
Related compounds
Custom attributes
(extracted from source data)
Target
Bacterial
Topo IV
Topo IV inhibitor
antibiotic
Topoisomerase
Pathway
Anti-infection
Microbiology&virology
DNA Damage/DNA Repair
Cell Cycle/DNA Damage
ATC
J01MA16
S01AE06
Toxicity type
cardiovascular
Therapeutic Class
Antiinfective Agents
Source data