General
Preferred name
GALANGIN
Synonyms
Norizalpinin ()
3,5,7-trihydroxyflavone ()
P&D ID
PD001197
CAS
548-83-4
Tags
available
drug candidate
natural product
nuisance
Drug indication
Discovery agent
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
A flavonoid found in high concentrations in Alpinia officinarum.
DESCRIPTION
Galangin (Norizalpinin) is an agonist/antagonist of the arylhydrocarbon receptor. Galangin (Norizalpinin) also shows inhibition of CYP1A1 activity.
PRICE
31
DESCRIPTION
A flavonol found in high concentrations in Alpinia officinarum and other members of the ginger family, that is used in traditional Chinese medicine.
(GtoPdb)
DESCRIPTION
Galangin is a naturally occuring flavonoid found in herbs. It is a well-known antioxidant and also an inhibitor of CYP1A1 activity. It is also an agonist/antagonist of the arylhydrocarbon receptor.
(Enamine Bioactive Compounds)
DESCRIPTION
Galangin (Norizalpinin) is an agonist/antagonist of the arylhydrocarbon receptor, and also shows inhibition of CYP1A1 activity.
(TargetMol Bioactive Compound Library)
DESCRIPTION
TRPC5 inhibitor
(Tocris Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
6
Organisms
5
Compound Sets
15
AdooQ Bioactive Compound Library
Cayman Chemical Bioactives
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
DrugMAP
Enamine Bioactive Compounds
EU-OPENSCREEN Bioactive Compound Library
Guide to Pharmacology
MedChem Express Bioactive Compound Library
Nuisance compounds in cellular assays
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
Tocris Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
33
Molecular Weight
270.05
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
3
Rotatable Bonds
1
Ring Count
3
Aromatic Ring Count
3
cLogP
2.58
TPSA
90.9
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.63
Structural alerts
1
Nonspecific/NOS
Flavonoid
Nuisance compounds
Related compounds
Custom attributes
(extracted from source data)
Pathway
Autophagy
MAPK
Metabolism
NF-κB
Metabolic Enzyme/Protease
Primary Target
TRPC
MOA
Inhibitor
Target
Cytochrome P450
P450 (e.g. CYP17)
ERK
Source data
