General
Preferred name
carbaryl
Synonyms
CARBARIL ()
1-Naphthalenol, methylcarbamate ()
1-naphthyl methylcarbamate ()
Sevin ()
Carylderm ()
Carbarilo ()
Suleo-C ()
Clinicide ()
ENT-23969 ()
NSC-27311 ()
Derbac-C ()
Derbac ()
Carbaryl-d7 ()
P&D ID
PD001177
CAS
27636-33-5
3197-92-0
11095-11-7
63-25-2
362049-56-7
Tags
available
drug
Drug Status
approved
withdrawn
experimental
Max Phase
4.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Carbaryl is the inhibitor for acetylcholinesterase that inhibits the degradation of acetylcholine in the synaptic cleft, leads to the accumulation of acetylcholine and causes neurotoxicity. Carbaryl can be used as an insecticide[1][2].
PRICE
29
DESCRIPTION
Incecticide. Carbaryl is a carbamate insecticide that inhibits acetylcholinesterase. Carbaryl has been used to control insects in agriculture.
(Enamine Bioactive Compounds)
DESCRIPTION
Carbaryl (1-naphthyl methylcarbamate) is a carbamate insecticide and parasiticide. It is a potent anticholinesterase agent belonging to the carbamate group of reversible cholinesterase inhibitors. It has a particularly low toxicity from dermal absorption and is used for control of head lice in some countries.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
1
Organisms
0
Compound Sets
16
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugCentral
DrugCentral Approved Drugs
Enamine Bioactive Compounds
Enamine BioReference Compounds
EU-OPENSCREEN Bioactive Compound Library
MedChem Express Bioactive Compound Library
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
44
Molecular Weight
201.08
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
1
Ring Count
2
Aromatic Ring Count
2
cLogP
2.56
TPSA
38.33
Fraction CSP3
0.08
Chiral centers
0.0
Largest ring
6.0
QED
0.77
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
AChR
Apoptosis
Cholinesterase (ChE)
Insecticide
Reactive Oxygen Species (ROS)
Reactive Oxygen Species
MOA
Acetylcholinesterase inhibitor
Pathway
Neuroscience
Immunology/Inflammation
Metabolic Enzyme/Protease
Neuronal Signaling
NF-κB
NF-¦ÊB
Source data
