General
Preferred name
Tricaprylin
Synonyms
CAPRYILIDENE ()
Trioctanoin ()
Glycerol Tri-n-octanoate ()
tricaprylic glyceride ()
Glyceryl trioctanoate ()
1,2,3-Trioctanoyl-rac-glycerol ()
AC-1202 ()
TRICAPRILIN ()
Glycerol trioctanoate, Glycerol tricaprylate, Trioctanoin, Tricaprylin ()
AC-1204 ()
Miglyol 808 ()
CER-0001 ()
NSC-4059 ()
Glyceryl tricaprylate ()
Axona ()
Caprylic triglyceride ()
Caprylic acid triglyceride ()
Tricapriline ()
Tricaprilina ()
1,2,3-Trioctanoyl Glycerol ()
1,2,3-Trioctanoyl Glycerol-13C3 ()
P&D ID
PD001167
CAS
114355-15-6
538-23-8
65402-55-3
Tags
available
drug candidate
Drug indication
Memory loss
memory impairment
Drug Status
investigational
Max Phase
3.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Tricaprilin (Trioctanoin) is an orally active and well tolerated ketogenic agent that safely induces ketosis. Tricaprilin restores brain electrical activity and metabolism to help counteract neuroinflammation in migraine. Tricaprilin is promising for research of migraine prevention and Alzheimer¡¯s disease (AD). Tricaprilin is a pure C8 medium chain triglyceride (MCT)[1][2][3].
PRICE 29
DESCRIPTION Tricaprilin (Glycerol Tri-n-octanoate) is used in study for patients with mild to moderate Alzheimer's disease. Tricaprilin also has a role as an anticonvulsant and a plant metabolite. (TargetMol Bioactive Compound Library)
Compound Sets
12
Cayman Chemical Bioactives
26952
29464
ChEMBL Drugs
CHEMBL1406148
Drug Repurposing Hub
DrugBank
DB12176
DrugMAP
DMNVFZA
DrugMatrix
MedChem Express Bioactive Compound Library
HY-B1804
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
glycerol-tri-n-octanoate
TargetMol Bioactive Compound Library
T5266
The Spectrum Collection
External IDs
49
Properties
(calculated by RDKit )
Molecular Weight
470.36
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
0
Rotatable Bonds
23
Ring Count
0
Aromatic Ring Count
0
cLogP
7.07
TPSA
78.9
Fraction CSP3
0.89
Chiral centers
0.0
Largest ring
0.0
QED
0.09
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Endogenous Metabolite
Indication
cosmetic
Pathway
Metabolism
Metabolic Enzyme/Protease
Source data