General
Preferred name
VILAZODONE HYDROCHLORIDE
Synonyms
SB659746A ()
EMD 68843 ()
Vilazodone HCl ()
Vilazodone (Hydrochloride) ()
EMD 68843 (Hydrochloride) ()
SB659746A (Hydrochloride) ()
EMD68843,SB659746A ()
Viibryd ()
SB659746-A ()
EMD-68843 ()
SB-659746-A ()
EMD 68 843 ()
Vilazodone (hydrochloride) ()
NGB 2904 (hydrochloride) ()
P&D ID
PD001156
CAS
163521-08-2
163521-12-8
189061-11-8
Tags
natural product
drug
available
Drug Status
approved
Max Phase
Phase 4
First approval
2011
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Long-acting beta2 agonist (LABA) (Tocris Bioactive Compound Library)
DESCRIPTION Vilazodone is a serotonin 5-HT1A partial agonist and serotonin-selective reuptake inhibitor (SPARI) that is used clinically as an antidepressant for major depressive disorder. (BOC Sciences Bioactive Compounds)
Compound Sets
9
BOC Sciences Bioactive Compounds
vilazodone-hydrochloride-cas-163521-08-2-item-84-452540
Cayman Chemical Bioactives
21547
21457
ChEMBL Approved Drugs
CHEMBL1615374
ChEMBL Drugs
CHEMBL1615374
MedChem Express Bioactive Compound Library
HY-14261
Selleckchem Bioactive Compound Library
vilazodone-hcl
TargetMol Bioactive Compound Library
T6232
The Spectrum Collection
Tocris Bioactive Compound Library
6202
External IDs
14
Properties
(calculated by RDKit )
Molecular Weight
477.19
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
2
Rotatable Bonds
7
Ring Count
5
Aromatic Ring Count
4
cLogP
4.45
TPSA
102.29
Fraction CSP3
0.31
Chiral centers
0.0
Largest ring
6.0
QED
0.38
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Neuroscience
Neuronal Signaling
Target
5-HT1A
SSRI
5-HT Receptor
Serotonin Transporter
5-HT Receptor,Serotonin Transporter
Primary Target
5-HT1A Receptors
MOA
Agonist
Source data