General
Preferred name
Manidipine
Synonyms
MANIDIPINE HYDROCHLORIDE ()
Franidipine ()
Artedil ()
Iperten ()
CV-4093 ()
Manidipine 2HCl ()
Manidipine dihydrochloride ()
Manidipine (dihydrochloride) ()
Manidipine (Manyper) ()
MANIDIPINE 6300 ()
CV-4093,(¡À)-Manidipine ()
Manidipine-d4 ()
P&D ID
PD001137
CAS
89226-75-5
89226-50-6
126229-12-7
120092-68-4
1189656-59-4
Tags
available
drug candidate
drug
Drug Status
investigational
approved
Drug indication
Discovery agent
Max Phase
Phase 3
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Manidipine (CV-4093) is dihydropyridine calcium channel blocker. (GtoPdb)
Compound Sets
16
AdooQ Bioactive Compound Library
A10554
Cayman Chemical Bioactives
23614
30768
ChEMBL Drugs
CHEMBL1085699
DrugBank
DB09238
DrugBank Approved Drugs
DB09238
DrugCentral
1631
DrugCentral Approved Drugs
1631
DrugMAP
DMJPGUA
DM983QP
DrugMatrix
Guide to Pharmacology
11739
MedChem Express Bioactive Compound Library
HY-17403
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
Manidipine(Manyper)
Manidipine-dihydrochloride(CV-4093)
TargetMol Bioactive Compound Library
T6577
T0193
The Spectrum Collection
External IDs
48
Properties
(calculated by RDKit )
Molecular Weight
610.28
Hydrogen Bond Acceptors
9
Hydrogen Bond Donors
1
Rotatable Bonds
10
Ring Count
5
Aromatic Ring Count
3
cLogP
4.95
TPSA
114.25
Fraction CSP3
0.31
Chiral centers
1.0
Largest ring
6.0
QED
0.19
Structural alerts
2
aggregator (Aggregator Advisor)
Aggregators
aggregator (ZINC)
Aggregators
Related compounds
Custom attributes
(extracted from source data)
Pathway
Neuronal Signaling
Membrane Transporter/Ion Channel
NF-κB
Target
Calcium Channel
Source data