General
Preferred name
tigecycline
Synonyms
Tigecycline (mesylate) ()
Tigecycline (hydrochloride) ()
GAR-936 mesylate ()
GAR-936 hydrochloride ()
GAR-936 ()
Tygacil ()
Tigecycline (tetramesylate) ()
GAR-936 tetramesylate ()
Tigecycline (GAR-936) ()
Tygacil, GAR-936, WAY-GAR-936, TBG-MINO ()
WAY-GAR-936 ()
Tigecycline-d9 ()
P&D ID
PD001132
CAS
220620-09-7
2699607-86-6
Tags
natural product
drug
available
Approved by
FDA
First approval
2005
Drug Status
approved
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
1
Compound Sets
17
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
Natural product-based probes and drugs
NCATS Inxight Approved Drugs
NPC Screening Collection
Other bioactive compounds
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
41
Properties
(calculated by RDKit )
Molecular Weight
585.28
Hydrogen Bond Acceptors
11
Hydrogen Bond Donors
7
Rotatable Bonds
6
Ring Count
4
Aromatic Ring Count
1
cLogP
0.51
TPSA
205.76
Fraction CSP3
0.52
Chiral centers
4.0
Largest ring
6.0
QED
0.18
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Bacterial
Autophagy
30S ribosome
antibiotic
Antineoplastic and Immunosuppressive Antibiotics,Autophagy,Bacterial
Pathway
Anti-infection
Microbiology&virology
MOA
ribosome inhibitor
Biosynthetic Origin
Polyketide (Aromatic)
Therapeutic Indication
Antibacterial
Therapeutic Class
Antimicrobial
Source data
