General
Preferred name
Amrinone
Synonyms
INAMRINONE ()
Wincoram ()
Inocor ()
INAMRINONE LACTATE ()
WIN-40680 ()
Cartonic ()
Amcoral ()
Cordemcura ()
Vesistol ()
C01CE01 ()
NSC-759805 ()
WIN 40680 ()
Amrinone Lactate ()
P&D ID
PD001084
CAS
60719-84-8
75898-90-7
Tags
natural product
drug
available
Approved by
FDA
First approval
1984
Drug Status
approved
Drug indication
Congestive heart failure
Cardiotonic
Cardiac disease
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Inamrinone is a phosphodiesterase inhibitor.
Marketed formulations may contain inamrinone lactate (PubChem CID 3035194). (GtoPdb)
Marketed formulations may contain inamrinone lactate (PubChem CID 3035194). (GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
2
Compound Sets
25
ChEMBL Approved Drugs
ChEMBL Drugs
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Enamine BioReference Compounds
EU-OPENSCREEN Bioactive Compound Library
Guide to Pharmacology
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
NCATS Inxight Approved Drugs
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
40
Properties
(calculated by RDKit )
Molecular Weight
187.07
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
1
Ring Count
2
Aromatic Ring Count
2
cLogP
1.02
TPSA
71.77
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.7
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Pathway
Apoptosis
Metabolism
Metabolic Enzyme/Protease
Target
PDE
TNF-??
PDE3A, PDE3B, PDE4B, TNF
Phosphodiesterase (PDE)
Indication
congestive heart failure
MOA
phosphodiesterase inhibitor
Therapeutic Class
Cardiovascular Agents
Source data