General
Preferred name
DIBEKACIN
Synonyms
Dibekacin Sulfate ()
P&D ID
PD001070
CAS
34493-98-6
Tags
natural product
drug
First approval
1979
Drug Status
approved
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Dibekacin is a semisynthetic derivative of (kanamycin B), with activity against Gram-positive and Gram-negative bacteria . It belongs to the aminoglycoside class of antibacterial compounds. (GtoPdb)
Compound Sets
9
ChEMBL Drugs
CHEMBL560976
Drug Repurposing Hub
DrugBank
DB13270
DrugBank Approved Drugs
DB13270
DrugCentral
855
DrugCentral Approved Drugs
855
Guide to Pharmacology
12134
NPC Screening Collection
The Spectrum Collection
External IDs
34
Properties
(calculated by RDKit )
Molecular Weight
451.26
Hydrogen Bond Acceptors
13
Hydrogen Bond Donors
9
Rotatable Bonds
6
Ring Count
3
Aromatic Ring Count
0
cLogP
-5.27
TPSA
247.94
Fraction CSP3
1.0
Chiral centers
13.0
Largest ring
6.0
QED
0.18
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Indication
gram-negative bacterial infections
MOA
bacterial 30S ribosomal subunit inhibitor
Source data