General
Preferred name
DEQUALINIUM CHLORIDE
Synonyms
Dequalinium chloride hydrate ()
DEQUALINIUM ()
Dequafungan ()
Danical ()
Decabis ()
Dequalinium dichloride ()
Dequalinium (Chloride) ()
Nordman ()
Dequacets ()
Dekamin ()
Chlorure de dequalinium ()
BAQD 10 ()
Dequadin ()
NSC-166454 ()
Labosept ()
Fluomizin ()
GNF-Pf-5483 ()
BAQD-10 ()
Decamine ()
Cloruro de decualinio ()
P&D ID
PD001065
CAS
6707-58-0
522-51-0
Tags
available
drug
Drug Status
approved
withdrawn
Max Phase
4.0
Drug indication
Bacterial vaginosis
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE 29
DESCRIPTION Selective blocker of apamin-sensitive K+ channels (LOPAC library)
DESCRIPTION Dequalinium Chloride is a PKC inhibitor with IC50 of 7-18 μM, and also a selective blocker of apamin-sensitive K+ channels with IC50 of 1.1 μM. (BOC Sciences Bioactive Compounds)
DESCRIPTION Dequalinium chloride (Decabis) , a topical bacteriostat, is a selective blocker of apamin-sensitive K+ channels. It is used in wound dressings and mouth infections and may also have antifungal action, but may cause skin ulceration. (TargetMol Bioactive Compound Library)
Cell lines
0
Organisms
4
Compound Sets
14
BOC Sciences Bioactive Compounds
dequalinium-chloride-cas-522-51-0-item-84-300567
Cayman Chemical Bioactives
17557
ChEMBL Approved Drugs
CHEMBL121663
ChEMBL Drugs
CHEMBL121663
CZ-OPENSCREEN Bioactive Library
DrugMatrix
EU-OPENSCREEN Bioactive Compound Library
EOS102343
Ki Database
Dequalinium
LOPAC library
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL121663
MedChem Express Bioactive Compound Library
HY-B0567
Prestwick Chemical Library
TargetMol Bioactive Compound Library
T0979
The Spectrum Collection
External IDs
24
Properties
(calculated by RDKit )
Molecular Weight
526.26
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
11
Ring Count
4
Aromatic Ring Count
4
cLogP
0.18
TPSA
59.8
Fraction CSP3
0.4
Chiral centers
0.0
Largest ring
6.0
QED
0.22
Structural alerts
2
aggregator (Aggregator Advisor)
Aggregators
aggregator (ZINC)
Aggregators
Related compounds
Custom attributes
(extracted from source data)
Target
PKC
Potassium Channel
Apoptosis
Bacterial
nAChR
Parasite
Pathway
Chromatin/Epigenetic
Cytoskeletal Signaling
Membrane Transporter/Ion Channel
Anti-infection
Neuronal Signaling
Source data