General
Preferred name
TENOXICAM
Synonyms
Ro-12-0068 ()
Tenoxicamum ()
Mobiflex ()
Tilcotil ()
NSC-758397 ()
RO 12-0068 ()
RO-12-0068/000 ()
Ro-120068000 ()
RO 12-0068/000 ()
P&D ID
PD001061
CAS
59804-37-4
Tags
available
drug
First approval
1987
Drug indication
rheumatic disease
Rheumatoid arthritis
Drug Status
approved
investigational
Max Phase
2.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Tenoxicam (Ro-12-0068), an antiinflammatory agent with analgesic and antipyretic properties.
PRICE 29
DESCRIPTION Tenoxicam is a non-steroidal anti-inflammatory drug (NSAID) that acts as a COX inhibitor. It demonstrates analgesic and antipyretic properties and has been used to clinically treat osteoarthritis or to control acute pain. (Enamine Bioactive Compounds)
DESCRIPTION Tenoxicam is a non-steroidal anti-inflammatory drug (NSAID).Tenoxicam is a good HO. radicals scavenger with an IC50 of 56.7 μM (BOC Sciences Bioactive Compounds)
DESCRIPTION Tenoxicam (Tilcotil), an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain. (TargetMol Bioactive Compound Library)
Cell lines
0
Organisms
1
Compound Sets
22
AdooQ Bioactive Compound Library
A10910
BOC Sciences Bioactive Compounds
tenoxicam-cas-59804-37-4-item-84-329685
Cayman Chemical Bioactives
20304
ChEMBL Drugs
CHEMBL302795
Drug Repurposing Hub
DrugBank
DB00469
DrugBank Approved Drugs
DB00469
DrugCentral
2595
DrugCentral Approved Drugs
2595
DrugMAP
DMVAZP9
DrugMAP Approved Drugs
DMVAZP9
DrugMatrix
Enamine Bioactive Compounds
EBC-04427
Enamine BioReference Compounds
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL302795
MedChem Express Bioactive Compound Library
HY-B0440
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
Tenoxicam(Mobiflex)
TargetMol Bioactive Compound Library
T1586
The Spectrum Collection
External IDs
30
Properties
(calculated by RDKit )
Molecular Weight
337.02
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
2
Rotatable Bonds
2
Ring Count
3
Aromatic Ring Count
2
cLogP
1.64
TPSA
99.6
Fraction CSP3
0.08
Chiral centers
0.0
Largest ring
6.0
QED
0.87
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
COX
PTGS1, PTGS2
Immunology & Inflammation related
Disease Area
rheumatology, orthopedics
Indication
rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, tendinitis, bursitis, periarthritis
MOA
cyclooxygenase inhibitor
Therapeutic Class
Antiinflammatory Agents
Pathway
Immunology/Inflammation
Neuroscience
Source data