General
Preferred name
PERGOLIDE MESYLATE
Synonyms
Pergolide methanesulfonate ()
CPD000058504 ()
LY127809 ()
Pergolide mesylate salt ()
Pergolide (mesylate) ()
NSC-319773 ()
LY-127809 ()
LY 127809 ()
Permax ()
NSC-758442 ()
Celance ()
Pergolide mesilate ()
P&D ID
PD001012
CAS
66104-23-2
66104-22-1
Tags
natural product
drug
available
Drug Status
approved
withdrawn
Max Phase
Phase 4
Drug indication
Dopamine Agonist
First approval
1988
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Dopamine receptor agonist; antiparkinsonian
(LOPAC library)
DESCRIPTION
Pergolide Mesylate is an antiparkinsonian agent which functions as a dopaminergic agonist.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
2
Compound Sets
13
AdooQ Bioactive Compound Library
Bioprocess diversity set
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
EU-OPENSCREEN Bioactive Compound Library
LOPAC library
MedChem Express Bioactive Compound Library
NIH Clinical Collections (NCC)
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
23
Molecular Weight
410.17
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
2
Rotatable Bonds
4
Ring Count
4
Aromatic Ring Count
2
cLogP
3.78
TPSA
73.4
Fraction CSP3
0.6
Chiral centers
3.0
Largest ring
6.0
QED
0.75
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
D2/D1
Biological process
rRNA & ncRNA processing
Pathway
Neuroscience
GPCR/G protein
Neuronal Signaling
Target
5-HT Receptor
Adrenergic Receptor
Dopamine Receptor
Source data
