General
Preferred name
THIRAM
Synonyms
Nobecutan ()
NSC-1771 ()
Rezifilm ()
NSC-622696 ()
SQ-1489 ()
Thirame ()
NSC-49512 ()
Tiramo ()
SQ 1489 ()
NSC-59637 ()
P&D ID
PD001000
CAS
12680-07-8
137-26-8
Tags
available
covalent binder
drug
Drug indication
Discovery agent
Parasitic infection
Drug Status
approved
experimental
investigational
Max Phase
2.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Thiram is the simplest thiuram disulfide and the oxidized dimer of dimethyldithiocarbamate. It is used as a fungicide, ectoparasiticide to prevent fungal diseases in seed and crops and similarly as an animal repellent to protect fruit trees and ornamentals from damage by rabbits, rodents and deer. Thiram may be used in dermatology as a scabicide. (Enamine Bioactive Compounds)
Cell lines
2
Organisms
2
Compound Sets
16
ChEMBL Drugs
CHEMBL120563
CovalentInDB
CI002346
CZ-OPENSCREEN Bioactive Library
Drug Repurposing Hub
DrugBank
DB13245
DrugBank Approved Drugs
DB13245
DrugCentral
3601
DrugCentral Approved Drugs
3601
DrugMAP
DMNXDGQ
DrugMatrix
Enamine Bioactive Compounds
EBC-04333
Enamine BioReference Compounds
NCATS Inxight Approved Drugs
0D771IS0FH
NIH Mechanistic Set
NPC Screening Collection
The Spectrum Collection
External IDs
30
Properties
(calculated by RDKit )
Molecular Weight
239.99
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
0
Rotatable Bonds
0
Ring Count
0
Aromatic Ring Count
0
cLogP
2.06
TPSA
6.48
Fraction CSP3
0.67
Chiral centers
0.0
Largest ring
0.0
QED
0.47
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Indication
contact dermatitis
Target
JAK2
Source data