General
Preferred name
NMDA
Synonyms
N-METHYL-D-ASPARTIC ACID ()
2-Methylamino-succinic acid(NMDA) ()
N-METHYL-D-ASPARTIC ACID (NMDA) ()
NMDA (N-Methyl-D-aspartic acid) ()
(R)-2-(Methylamino)Succinic Acid ()
Nmda ()
2-Methylamino-Succinic Acid ()
N-Methyl-Daspartate ()
P&D ID
PD000968
CAS
6384-92-5
Tags
drug candidate
natural product
available
Drug indication
Discovery agent
Drug Status
investigational
Max Phase
Phase 2
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION NMDA glutamate receptor agonist (LOPAC library)
Cell lines
0
Organisms
1
Compound Sets
17
AdooQ Bioactive Compound Library
A12751
Axon Medchem Screening Library
3472
Cayman Chemical Bioactives
14581
ChEMBL Drugs
CHEMBL291278
Concise Guide to Pharmacology 2017/18
4268
Concise Guide to Pharmacology 2019/20
4268
Concise Guide to Pharmacology 2021/22
4268
Concise Guide to Pharmacology 2023/24
4268
Drug Repurposing Hub
DrugMAP
DMKP6BM
EU-OPENSCREEN Bioactive Compound Library
EOS101359
Guide to Pharmacology
4268
LOPAC library
MedChem Express Bioactive Compound Library
HY-17551
Selleckchem Bioactive Compound Library
nmda-n-methyl-d-aspartic-acid
TargetMol Bioactive Compound Library
T6608
The Spectrum Collection
External IDs
32
Properties
(calculated by RDKit )
Molecular Weight
147.05
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
3
Rotatable Bonds
4
Ring Count
0
Aromatic Ring Count
0
cLogP
-0.87
TPSA
86.63
Fraction CSP3
0.6
Chiral centers
1.0
Largest ring
0.0
QED
0.48
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
NMDA
Pathway
Neuroscience
Membrane Transporter/Ion Channel
Metabolic Enzyme/Protease
Neuronal Signaling
Target
NMDA Receptor
GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D
NMDA agonist
Endogenous Metabolite
iGluR
NMDAR
MOA
glutamate receptor agonist
Source data