General
Preferred name
OXFENDAZOLE
Synonyms
RS-8858 ()
Oxfendazol ()
RS-8858,Fenbendazole sulfoxide ()
Synanthic ()
NSC-758943 ()
P&D ID
PD000960
CAS
53716-50-0
Tags
available
drug
Approved by
FDA
Drug indication
Trichuris infection
infection
Drug Status
vet_approved
approved
investigational
Max Phase
2.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Oxfendazole is a sulfoxide form of fenbendazole that is effective when taken orally. Oxfendazole fights parasites and has tumor-promoting activity[1][2][3].
PRICE 29
DESCRIPTION Oxfendazole (RS-8858), a broad spectrum benzimidazole anthelmintic, protects livestock against roundworm, strongyles and pinworms. (TargetMol Bioactive Compound Library)
Compound Sets
15
Cayman Chemical Bioactives
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugMAP
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
NPC Screening Collection
Pandemic Response Box
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
External IDs
37
Properties
(calculated by RDKit )
Molecular Weight
315.07
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
3
Aromatic Ring Count
3
cLogP
2.91
TPSA
84.08
Fraction CSP3
0.07
Chiral centers
1.0
Largest ring
6.0
QED
0.78
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
Glucose uptake inhibitor
Parasite
Tubulin chain
Pathway
Cytoskeletal Signaling
Metabolism
Microbiology/virology
Anti-infection
Source data