General
Preferred name
ASPARTAME
Synonyms
SC-18862 ()
SC-18862,Nutrasweet ()
Nutrasweet ()
Zero-cal ()
Aspartamo ()
Methyl aspartylphenylalanate ()
Pal sweet ()
Aspartame (e951) ()
APM ()
E951 ()
Aspartam ()
Ins-951 ()
NSC-758953 ()
Sladex ()
E-951 ()
Ins no.951 ()
P&D ID
PD000953
CAS
22839-47-0
Tags
available
drug candidate
Drug Status
nutraceutical
investigational
Max Phase
3.0
Drug indication
Sweetener
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
HALF-LIFE At room temperature, aspartame is most stable at pH 4.3, where its half-life is nearly 300 days. At pH 7, its half-life is shortened to only a few days.
Compound Sets
9
Cayman Chemical Bioactives
26089
ChEMBL Drugs
CHEMBL171679
Drug Repurposing Hub
DrugBank
DB00168
MedChem Express Bioactive Compound Library
HY-B0361
ReFrame library
Selleckchem Bioactive Compound Library
aspartame
TargetMol Bioactive Compound Library
T0697
The Spectrum Collection
External IDs
42
Properties
(calculated by RDKit )
Molecular Weight
294.12
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
3
Rotatable Bonds
7
Ring Count
1
Aromatic Ring Count
1
cLogP
-0.31
TPSA
118.72
Fraction CSP3
0.36
Chiral centers
2.0
Largest ring
6.0
QED
0.59
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Taste receptor
Transient receptor potential cation channel
TAS1R2, TRPV1
Source data