General
Preferred name
REBAMIPIDE
Synonyms
Opc 12759 ()
Proamipide ()
OPC12759 ()
Mucosta ()
rebamipide (ophthalmic) ()
OPC-12759,Proamipide ()
NSC-758955 ()
Rebator ()
OPC-12759 ()
Rebamipide-d4 ()
P&D ID
PD000950
CAS
111911-87-6
90098-04-7
1219409-06-9
Tags
natural product
drug
available
Approved by
PMDA
First approval
2011
Drug Status
investigational
approved
Drug indication
Peptic ulcer
Max Phase
Phase 3
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Rebamipide is an amino acid derivative of 2-(1H)-quinolinone with gastroprotective action .
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
17
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMatrix
Guide to Pharmacology
MedChem Express Bioactive Compound Library
Natural product-based probes and drugs
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
34
Molecular Weight
370.07
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
3
Rotatable Bonds
5
Ring Count
3
Aromatic Ring Count
3
cLogP
2.61
TPSA
99.26
Fraction CSP3
0.11
Chiral centers
1.0
Largest ring
6.0
QED
0.64
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
oxidation-reduction
Immunology/Inflammation
Target
Free radical scavengers
COX
CCK Receptor
Biosynthetic Origin
Other (Amino Acid)
Therapeutic Indication
Antiulcer
Source data
