General
Preferred name
PROTIONAMIDE
Synonyms
Protionamidum ()
Prothionamide ()
1321-TH ()
Prothionamide, 1321-TH ()
RP 9778 ()
RP-9778 ()
Peteha ()
Trevintix ()
NSC-758962 ()
TH-1321 ()
Ektebin ()
P&D ID
PD000945
CAS
14222-60-7
Tags
natural product
drug
available
Drug Status
investigational
approved
Drug indication
Tuberculosis
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
An anti-tuberculosis agent. It has also been used to treat Leprosy. Antibacterial (tuberculostatic).
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
18
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
MedChem Express Bioactive Compound Library
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
31
Molecular Weight
180.07
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
3
Ring Count
1
Aromatic Ring Count
1
cLogP
1.67
TPSA
38.91
Fraction CSP3
0.33
Chiral centers
0.0
Largest ring
6.0
QED
0.72
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Microbiology&virology
Anti-infection
Target
antibiotic
Bacterial
MOA
Antibiotic
Indication
tuberculosis
Therapeutic Class
Antituberculosis Agents
Source data
