General
Preferred name
CEPHARANTHINE
Synonyms
NSC-623442 ()
(+)-Cepharanthine ()
P&D ID
PD000940
CAS
481-49-2
Tags
natural product
drug
available
Approved by
PMDA
First approval
1951
Drug indication
Thrombocytopenia
Drug Status
investigational
approved
Max Phase
Phase 2
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
12
Organisms
2
Compound Sets
14
Cayman Chemical Bioactives
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
MedChem Express Bioactive Compound Library
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
30
Properties
(calculated by RDKit )
Molecular Weight
606.27
Hydrogen Bond Acceptors
8
Hydrogen Bond Donors
0
Rotatable Bonds
2
Ring Count
9
Aromatic Ring Count
4
cLogP
6.87
TPSA
61.86
Fraction CSP3
0.35
Chiral centers
2.0
Largest ring
18.0
QED
0.25
Structural alerts
2
aggregator (Aggregator Advisor)
Aggregators
aggregator (ZINC)
Aggregators
Related compounds
Custom attributes
(extracted from source data)
Pathway
Apoptosis
Anti-infection
Metabolic Enzyme/Protease
Target
TNF-??
TNF-¦Á
Cytochrome P450
Parasite
SARS-CoV
TNF-alpha
MOA
TNF
NFkB pathway inhibitor
Source data
