General
Preferred name
SECURININE
Synonyms
(-)-Securinine ()
Securinin ()
Securinina ()
L-securinine ()
Securinan-11-one ()
NSC-107413 ()
P&D ID
PD000928
CAS
5610-40-2
Tags
available
drug candidate
Drug Status
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
(-)-Securinine is plant-derived alkaloid and also a GABAA receptor antagonist.
PRICE
41
DESCRIPTION
(-)-Securinine (Securinine) is plant-derived alkaloid and also a GABAA receptor antagonist.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
6
Organisms
0
Compound Sets
6
ChEMBL Drugs
Drug Repurposing Hub
MedChem Express Bioactive Compound Library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
26
Molecular Weight
217.11
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
0
Rotatable Bonds
0
Ring Count
4
Aromatic Ring Count
0
cLogP
1.41
TPSA
29.54
Fraction CSP3
0.62
Chiral centers
3.0
Largest ring
6.0
QED
0.57
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
GABA Receptor
GABAA
GABRA1
MOA
GABA receptor antagonist, TP53 activator
Pathway
Membrane Transporter/Ion Channel
Neuroscience
Neuronal Signaling
Source data
