General
Preferred name
PD000923
Synonyms
7-NITROINDAZOLE ()
7-NINA ()
7-NITROINDAZOLE, SODIUM SALT ()
7-nitro-1H-indazole ()
7NI ()
P&D ID
PD000923
CAS
2942-42-9
161467-34-1
Tags
available
drug candidate
Drug indication
Discovery agent
Drug Status
experimental
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
29
DESCRIPTION
Non-selective NOS inhibitor
(Tocriscreen Plus)
DESCRIPTION
Selective inhibitor of brain nitric oxide synthase
(LOPAC library)
DESCRIPTION
Non-selective NOS inhibitor
(Tocriscreen Total)
DESCRIPTION
7-Nitroindazole is a non-selective inhibitor of NOS (Nitric oxide synthase) isoforms.
(Enamine Bioactive Compounds)
DESCRIPTION
7-Nitroindazole is a non-selective inhibitor of NOS isoforms in vitro for neuronal nitric oxide synthase showing a 10-fold selectivity for neuronal NOS.
(TargetMol Bioactive Compound Library)
DESCRIPTION
Non-selective NOS inhibitor. Sodium salt of 7-nitroindazole (Cat. No. 0602)
(Tocriscreen Total)
DESCRIPTION
7-NINA is a non-selective NOS inhibitor.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
21
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
Drug Repurposing Hub
DrugBank
DrugMAP
DrugMatrix
Enamine Bioactive Compounds
Enamine BioReference Compounds
Guide to Pharmacology
LOPAC library
NIH Clinical Collections (NCC)
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
Tocriscreen Plus
Tocriscreen Total
ZINC Tool Compounds
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
46
Molecular Weight
163.04
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
1
Ring Count
2
Aromatic Ring Count
2
cLogP
1.47
TPSA
71.82
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.51
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target Type
Enzymes
Selectivity
nNOS
Target
NOS
NOS1, NOS2, NOS3
MOA
nitric oxide synthase inhibitor
Pathway
Immunology/Inflammation
Source data
