General
Preferred name
TRYPTAMINE
Synonyms
TRYPTAMINE HYDROCHLORIDE ()
Tryptamine HCl ()
Tryptamine-d4 (hydrochloride) ()
P&D ID
PD000807
CAS
61-54-1
340257-60-5
Tags
drug candidate
natural product
available
Drug Status
experimental
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Tryptamine is a monoamine alkaloid acting as a neuromodulator. It is an agonist of hTAAR1. It acts as a non-selective serotonin receptor agonist and serotonin-norepinephrine-dopamine releasing agent (SNDRA). (BOC Sciences Bioactive Compounds)
DESCRIPTION Serotonin receptor ligand (LOPAC library)
Cell lines
0
Organisms
1
Compound Sets
15
BOC Sciences Bioactive Compounds
tryptamine-cas-61-54-1-292494
Cayman Chemical Bioactives
20995
33682
33538
Concise Guide to Pharmacology 2017/18
125
Concise Guide to Pharmacology 2019/20
125
Concise Guide to Pharmacology 2021/22
125
Concise Guide to Pharmacology 2023/24
125
DrugBank
DB08653
DrugMAP
DMAFPHB
EU-OPENSCREEN Bioactive Compound Library
EOS102364
Guide to Pharmacology
125
Ki Database
TRYPTAMINE
LOPAC library
Selleckchem Bioactive Compound Library
tryptamine
TargetMol Bioactive Compound Library
T0647
The Spectrum Collection
External IDs
54
Properties
(calculated by RDKit )
Molecular Weight
160.1
Hydrogen Bond Acceptors
1
Hydrogen Bond Donors
2
Rotatable Bonds
2
Ring Count
2
Aromatic Ring Count
2
cLogP
1.67
TPSA
41.81
Fraction CSP3
0.2
Chiral centers
0.0
Largest ring
6.0
QED
0.69
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Membrane Transporter/Ion Channel
Metabolism
Neuroscience
Target
5-HT
AADH
hTRPA1
TAAR
Source data