General
Preferred name
BROMPHENIRAMINE MALEATE
Synonyms
(±)-Brompheniramine maleate ()
Dimetane ()
Rolabromophen ()
Dimotane ()
Brompheniramine hydrogen maleate ()
BROMPHENIRAMINE ()
Brompheniramine (maleate) ()
(±)-Brompheniramine (maleate) ()
Dimotane L.A. ()
Dimetane-Ten ()
Brompheniramine fumarate ()
(+)-Brompheniramine Maleate ()
Parabromdylamine Maleate ()
NSC-758652 ()
Dimegan ()
P&D ID
PD000778
CAS
980-71-2
86-22-6
102282-22-4
32865-01-3
Tags
natural product
drug
available
Drug Status
approved
Max Phase
Phase 4
Drug indication
Antihistaminic
First approval
1957
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION H1 Histamine receptor antagonist (LOPAC library)
DESCRIPTION Brompheniramine hydrogen maleate is a histamine H1 receptors antagonist. (BOC Sciences Bioactive Compounds)
Cell lines
0
Organisms
1
Compound Sets
11
AdooQ Bioactive Compound Library
A11699
BOC Sciences Bioactive Compounds
brompheniramine-hydrogen-maleate-cas-980-71-2-349427
Cayman Chemical Bioactives
20996
ChEMBL Approved Drugs
CHEMBL1200961
ChEMBL Drugs
CHEMBL1200961
LOPAC library
MedChem Express Bioactive Compound Library
HY-B0480
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
brompheniramine
TargetMol Bioactive Compound Library
T0205
The Spectrum Collection
External IDs
19
Properties
(calculated by RDKit )
Molecular Weight
434.08
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
2
Rotatable Bonds
7
Ring Count
2
Aromatic Ring Count
2
cLogP
3.64
TPSA
90.73
Fraction CSP3
0.25
Chiral centers
1.0
Largest ring
6.0
QED
0.65
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
H1
Pathway
GPCR/G protein
Neuroscience
Immunology/Inflammation
Membrane Transporter/Ion Channel
Neuronal Signaling
Target
HT
Calcium Channel
Histamine Receptor
mAChR
Potassium Channel
Sodium Channel
Source data